Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834895 | 0.92 | KDR (0.61) | KDRPDGFRB | |
| SCHEMBL848782 | 0.92 | KDR (0.61) | KDRPDGFRB | |
| SCHEMBL837369 | 0.89 | KDR (0.58) | KDRPDGFRB | |
| SCHEMBL12751013 | 0.89 | KDR (0.58) | KDRPDGFRB | |
| SCHEMBL835523 | 0.88 | KDR (0.56) | KDRPDGFRB | |
| SCHEMBL12751011 | 0.88 | KDR (0.56) | KDRPDGFRB | |
| SCHEMBL15810034 | 0.86 | KDR (0.55) | KDRPDGFRB | |
| SCHEMBL835335 | 0.86 | KDR (0.55) | KDRPDGFRB | |
| SCHEMBL835091 | 0.86 | KDR (0.55) | KDRPDGFRB | |
| SCHEMBL12751064 | 0.85 | KDR (0.55) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099757-B1 | SULFOXIMINES AS KINASE INHIBITORS | ALLERGAN INC (US) | 2014-06-25 | — | — | EP | disclosed |
| WO-2010078393-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2010-07-08 | — | — | WO | disclosed |