SCHEMBL347181

SCHEMBL347181

[InH3].c1ccc(-c2nccc3ccccc23)cc1.c1ccc(-c2nccc3ccccc23)cc1.c1ccc(-c2nccc3ccccc23)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.64
NPC1 O15118 3/20 0.64
RAB9A P51151 3/20 0.64
MAPT P10636 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
KMT2A Q03164 2/20 0.64
GLA P06280 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
GPR55 Q9Y2T6 1/20 0.63
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2C19 P33261 2/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
CYP1A2 P05177 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
ATM Q13315 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50715 0.98 KDM4E (0.66) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL29398625 0.98 KDM4E (0.66) KDM4ENPC1RAB9AMAPTL3MBTL1
Hydrochloric Acid SCHEMBL3320794 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL30090880 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL29489796 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL1686110 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL30464099 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL29400645 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL31275980 0.96 KDM4E (0.69) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL30497069 0.96 KDM4E (0.64) KDM4ENPC1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2243177-A1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS Global OLED Technology LLC (US) 2010-10-27 EP claimed
EP-2158290-A1 PHOSPHORESCENT OLED HAVING DOUBLE EXCITON-BLOCKING LAYERS EASTMAN KODAK COMPANY (US) 2010-03-03 EP claimed
WO-2009097108-A1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS EASTMAN KODAK COMPANY (US) 2009-08-06 WO claimed
WO-2008156554-A1 PHOSPHORESCENT OLED HAVING DOUBLE EXCITON-BLOCKING LAYERS EASTMAN KODAK COMPANY (US) 2008-12-24 WO claimed
EP-3155669-B1 METHOD FOR FABRICATING A LED PACKAGE WITH RED-EMITTING PHOSPHORS CURRENT LIGHTING SOLUTIONS LLC (US) 2024-03-27 EP disclosed
US-10968229-B2 Seven-membered ring compounds IDEMITSU KOSAN CO., LTD. (JP) 2021-04-06 US disclosed
CN-109845404-B Display device and method for manufacturing the same 夏普株式会社 2020-11-20 CN disclosed
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2019-04-25 US disclosed
US-20160372687-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2016-12-22 US disclosed
US-9458182-B2 Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics BASF SE (DE) 2016-10-04 US disclosed
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-01-19 US disclosed
EP-2385940-A1 2,4,6-TRI-(HETEROARYLPHENYL)-PYRIDINES AND ELECTRON-TRANSPORTING MATERIALS COMPRISING THEM General Electric Company (US) 2011-11-16 EP disclosed
US-8041982-B2 Real time clock TEXAS INSTRUMENTS INCORPORATED (US) 2011-10-18 US disclosed
US-20100308308-A1 USE OF SUBSTITUTED TRIS(DIPHENYLAMINO)TRIAZINE COMPOUNDS IN OLEDS BASF SE (DE) 2010-12-09 US disclosed
WO-2010080471-A1 2,4,6-TRI-(HETEROARYLPHENYL)-PYRIDINES AND ELECTRON-TRANSPORTING MATERIALS COMPRISING THEM GENERAL ELECTRIC COMPANY (US) 2010-07-15 WO disclosed
WO-2007071450-A1 ELECTRONIC DEVICE WITH A LAYER STRUCTURE OF ORGANIC LAYERS NOVALED AG (DE) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS MCM7, XPO7, LUC7L2 KDM4E 2621/4885NPC1 923/4885RAB9A 100/4885
US-10968229-B2 Seven-membered ring compounds MCM7, XPO7, LUC7L2 KDM4E 2621/4885NPC1 923/4885RAB9A 100/4885
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS DDT, CDKL1, CDK2 KDM4E 2857/4885NPC1 4516/4885RAB9A 3555/4885
US-20160372687-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES DDT, OCIAD1, OCIAD2 KDM4E 2365/4885NPC1 4696/4885RAB9A 3618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.