SCHEMBL3472876

SCHEMBL3472876

CC(C)C(=O)Nc1ncnc2c1ncn2[C@H]1CC(O)[C@@H](CO)O1

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.62
▸ SLC29A1 Q99808 1/20 0.58
▸ ADORA3 P0DMS8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9078717 0.91 HIF1A (0.58) HIF1ASLC29A1ADORA3
SCHEMBL9078711 0.91 HIF1A (0.58) HIF1ASLC29A1ADORA3
SCHEMBL9078704 0.91 HIF1A (0.58) HIF1ASLC29A1ADORA3
SCHEMBL26791270 0.90 KDM4E (0.49) HIF1ASLC29A1ADORA3
SCHEMBL21011332 0.90 HIF1A (0.67) HIF1ASLC29A1ADORA3
SCHEMBL21011330 0.90 HIF1A (0.67) HIF1ASLC29A1ADORA3
SCHEMBL30011905 0.90 HIF1A (0.67) HIF1ASLC29A1ADORA3
SCHEMBL21545786 0.88 HIF1A (0.64) HIF1ASLC29A1ADORA3
SCHEMBL10486831 0.87 PNP (0.52) HIF1A
SCHEMBL26801105 0.87 PNP (0.52) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100280234-A1 Photocleavable Protecting Groups and Methods for Their Use AFFYMETRIX, INC. (US) 2010-11-04 — — US disclosed
US-7470783-B2 Photocleavable protecting groups and methods for their use AFFYMETRIX, INC. (US) 2008-12-30 — — US disclosed
US-20050266148-A1 Photocleavable protecting groups and methods for their use AFFYMETRIX, INC., A DELAWARE CORPORATION 2005-12-01 — — US disclosed
US-6881836-B2 Photocleavable protecting groups and methods for their use AFFYMETRIX, INC (US) 2005-04-19 — — US disclosed
US-20030144499-A1 Photocleavable protecting groups and methods for their use AFFYMETRIX, INC. (US) 2003-07-31 — — US disclosed
US-6566515-B1 Performing photochemical reactions on a surface; prepare chemical mixture, apply to surface, irradiate, monitor generation of reaction product AFFYMETRIX, INC. 2003-05-20 — — US disclosed
US-6147205-A ARYLALKYLOXYCARBONYL GROUPS; FOR SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES AND POLYPEPTIDES AFFYMETRIX, INC. (US) 2000-11-14 — — US disclosed
WO-1998039348-A9 PHOTOCLEAVABLE PROTECTING GROUPS AND METHODS FOR THEIR USE — 1999-02-18 — — WO disclosed
WO-1998039348-A1 PHOTOCLEAVABLE PROTECTING GROUPS AND METHODS FOR THEIR USE AFFYMETRIX, INC. (US) 1998-09-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100280234-A1 Photocleavable Protecting Groups and Methods for Their Use RNF168, RTCB, C9 HIF1A 1573/4885SLC29A1 2265/4885ADORA3 768/4885
US-20030144499-A1 Photocleavable protecting groups and methods for their use RTCB, RRS1, GAR1 HIF1A 2099/4885SLC29A1 1364/4885ADORA3 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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