SCHEMBL3473868

SCHEMBL3473868

NC=Cc1ccccc1.[SiH4]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.55
CYP19A1 P11511 2/20 0.52
MAOA P21397 2/20 0.52
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
NFE2L2 Q16236 1/20 0.46
TRPA1 O75762 1/20 0.46
ALOX5 P09917 1/20 0.46
MAPK1 P28482 1/20 0.46
IDO1 P14902 2/20 0.44
HDAC3 O15379 1/20 0.44
TNKS O95271 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3473863 1.00 MAOB (0.55) MAOBCYP19A1MAOAALDH1A1LMNA
SCHEMBL26103 0.97
SCHEMBL12992402 0.97
SCHEMBL26102 0.97
Hydrochloric Acid SCHEMBL2024092 0.94 MAOB (0.55) MAOBCYP19A1MAOAALDH1A1LMNA
Water SCHEMBL27280460 0.94 MAOB (0.55) MAOBCYP19A1MAOAALDH1A1LMNA
Phosphine SCHEMBL29272693 0.94 MAOB (0.55) MAOBCYP19A1MAOAALDH1A1LMNA
(Z)-1,2-Diphenylethene SCHEMBL29141136 0.94 MAOB (0.59) MAOBCYP19A1MAOANFE2L2TRPA1
Bromide SCHEMBL28992232 0.94 MAOB (0.55) MAOBCYP19A1MAOAALDH1A1LMNA
Butadiene SCHEMBL25208255 0.87 MAOB (0.48) MAOBCYP19A1MAOAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5450513-A Silane-treated optical components CORNING INCORPORATED (US) 1995-09-12 US claimed
US-20100294363-A1 Coated Polyester Film For Lamination to Ethylene-Vinyl Acetate Layers MITSUBISHI POLYESTER FILM, INC. (US) 2010-11-25 US disclosed
US-5738793-A USING ZEOLITES COATED WITH SILANE COMPOUNDS AS SOLID SORBENTS TEXACO INC. (US) 1998-04-14 US disclosed
US-5450513-A Silane-treated optical components CORNING INCORPORATED (US) 1995-09-12 US disclosed