Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19000 | 1.00 | — | — | |
| Water SCHEMBL6696034 | 0.82 | — | — | |
| Water SCHEMBL11239599 | 0.82 | — | — | |
| Bromide SCHEMBL9421218 | 0.82 | — | — | |
| Bromide SCHEMBL21063374 | 0.82 | — | — | |
| Bromide SCHEMBL7639809 | 0.82 | — | — | |
| Bromide SCHEMBL812148 | 0.82 | — | — | |
| Bromide SCHEMBL22158252 | 0.82 | — | — | |
| Water SCHEMBL840153 | 0.82 | — | — | |
| Bromide SCHEMBL16290293 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020054873-A1 | METHOD FOR PRODUCING FIBROIN SOLUTION AND METHOD FOR PRODUCING PROTEIN MOLDED BODY | Ｓｐｉｂｅｒ株式会社 | 2020-03-19 | — | — | WO | disclosed |
| EP-2788326-B1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RES & DEV (FR) | 2019-04-24 | — | — | EP | disclosed |
| CN-109071534-A | BROMODOMAIN INHIBITORS | 艾伯维公司 | 2018-12-21 | — | — | CN | disclosed |
| US-9732044-B2 | N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-08-15 | — | — | US | disclosed |
| US-20170066725-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-03-09 | — | — | US | disclosed |
| US-9452120-B2 | N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-09-27 | — | — | US | disclosed |
| EP-2788326-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | Galderma Research & Development (FR) | 2014-10-15 | — | — | EP | disclosed |
| US-20140234245-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-08-21 | — | — | US | disclosed |
| US-8703805-B2 | Modulators of LXR | EXELIXIS PATENT COMPANY LLC (US) | 2014-04-22 | — | — | US | disclosed |
| WO-2013064681-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-05-10 | — | — | WO | disclosed |
| CN-100577702-C | Propylene block copolymer | MITSUBISHI CHEM CORP | 2010-01-06 | — | — | CN | disclosed |
| EP-1910307-A1 | PYRAZOLE BASED LXR MODULATORS | Exelixis, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002559-A1 | PYRAZOLE BASED LXR MODULATORS | EXELIXIS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| CN-1823104-A | Propylene block copolymer | MITSUBISHI CHEM CORP (JP) | 2006-08-23 | — | — | CN | disclosed |
| EP-0597423-B1 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6011150-A | SYNTHETIC INTERMEDIATE OF A 1 BETA-METHYLCARBAPENEM DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| US-5847115-A | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5631363-A | ANTIBIOTIC INTERMEDIATE | TANABE SEIYAKU CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5442055-A | Chemical intermediates for carbapenicillins | TANABE SEIYAKU CO., LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0597423-A2 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |