Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.90 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469378 | 1.00 | ALOX5AP (0.90) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL502930 | 0.95 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL10266138 | 0.95 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL3467194 | 0.95 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL3462814 | 0.94 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL4192374 | 0.94 | ALOX5AP (0.94) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL4203820 | 0.94 | ALOX5AP (1.00) | ALOX5APALOX5 | |
| SCHEMBL4193522 | 0.93 | ALOX5AP (0.85) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL168991 | 0.93 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL176475 | 0.93 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144875-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | Amira Pharmaceuticals, Inc. (US) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008137609-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |