Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43340 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL6045196 | 0.84 | — | — | |
| Ammonia Solution, Strong SCHEMBL9178426 | 0.84 | — | — | |
| Bromide SCHEMBL5490790 | 0.84 | — | — | |
| SCHEMBL29061039 | 0.84 | — | — | |
| SCHEMBL27643070 | 0.84 | — | — | |
| Acetic Acid SCHEMBL28175735 | 0.81 | PAOX (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| Acetic Acid SCHEMBL538702 | 0.81 | PAOX (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| Benzene SCHEMBL27940486 | 0.77 | PAOX (0.56) | PAOXKDM4EMAPK1HIF1ATSHR | |
| Trifluoroacetic Acid SCHEMBL22578596 | 0.77 | PAOX (0.50) | PAOXKDM4EMAPK1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032165-A2 | PRODRUGS OF ARTEMISININ | NORTH-WEST UNIVERSITY (ZA) | 2010-03-25 | — | — | WO | disclosed |