Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723629 | 0.79 | PIK3CD (0.47) | PIK3CDCYP1A2TDP1KMT2AKDM4E | |
| SCHEMBL4724913 | 0.79 | PIK3CD (0.47) | PIK3CDCYP1A2TDP1KMT2AKDM4E | |
| SCHEMBL6188158 | 0.78 | KDM4E (0.44) | CYP1A2TDP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6187621 | 0.78 | ATM (0.41) | KMT2AKDM4ESMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL1105150 | 0.78 | CYP1A2 (0.54) | PIK3CDCYP1A2TDP1KMT2AKDM4E | |
| SCHEMBL378021 | 0.76 | CYP1A2 (0.52) | PIK3CDCYP1A2TDP1KMT2AKDM4E | |
| SCHEMBL21074578 | 0.76 | CYP1A2 (0.52) | PIK3CDCYP1A2TDP1KMT2AKDM4E | |
| SCHEMBL4908778 | 0.76 | MAOB (0.43) | KMT2AKDM4ESMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL19701915 | 0.74 | PIK3CD (0.50) | PIK3CDCYP1A2TDP1KMT2AKDM4E | |
| SCHEMBL22212138 | 0.74 | PIK3CD (0.50) | PIK3CDCYP1A2TDP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | claimed |
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |