Cyclohexane

Cyclohexane

SCHEMBL347610

C1CCCCC1.C=C(C)C(N)=O.C=C(C)C(N)=O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.80
LMNA P02545 3/20 0.44
BLM P54132 2/20 0.44
ALOX15 P16050 1/20 0.44
PMP22 Q01453 1/20 0.44
ALDH1A1 P00352 5/20 0.36
LDHA P00338 2/20 0.33
LDHB P07195 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CRBN Q96SW2 1/20 0.32
OR51E2 Q9H255 1/20 0.31
EPHX1 P07099 1/20 0.31
TSHR P16473 1/20 0.30
FGFR4 P22455 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL2887999 1.00 TDP1 (0.80) TDP1LMNABLMALOX15PMP22
SCHEMBL1905147 1.00 TDP1 (0.80) TDP1LMNABLMALOX15PMP22
Cyclohexane SCHEMBL10642803 0.97 TDP1 (0.75) TDP1LMNABLMALOX15PMP22
SCHEMBL14870 0.89
SCHEMBL2128293 0.89 TDP1 (1.00) TDP1LMNABLMALOX15PMP22
SCHEMBL5708652 0.89 TDP1 (1.00) TDP1LMNABLMALOX15PMP22
Cyclohexane SCHEMBL11172203 0.87 TDP1 (0.60) TDP1LMNABLMALOX15PMP22
Methyl Alcohol SCHEMBL8853832 0.86
Acetamide SCHEMBL10598982 0.86 TDP1 (0.92) TDP1LMNABLMALOX15PMP22
Ammonia Solution, Strong SCHEMBL21838781 0.86 TDP1 (0.92) TDP1LMNABLMALOX15PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
EP-4121803-A1 EMBEDDED SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2023-01-25 EP claimed
WO-2021186383-A1 EMBEDDED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-09-23 WO claimed
CN-112646092-A Preparation method of magnetic microspheres with uniform particle size 南京亘闪生物科技有限公司 2021-04-13 CN claimed
EP-3200840-A1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES Novartis AG (CH) 2017-08-09 EP claimed
WO-2016100190-A1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES NOVARTIS AG (CH) 2016-06-23 WO claimed
US-20050276781-A1 Molecularly imprinted phosphate binders for therapeutic use UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2005-12-15 US claimed
US-5278243-A Polysiloxanes SOANE TECHNOLOGIES, INC. (US) 1994-01-11 US claimed
US-4537855-A PHOTOPOLYMERIZABLE HIGH MOLECULAR WEIGHT COMPOUND HAVING POLYFUCTIONAL ETHYLENICALLY UNSATURATED SIDE CHAIN OR END GROUPS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-08-27 US claimed
US-4508884-A COPOLYMER OF UNSATURATED SILICONE ESTER, UNSATURATED ESTER, HYDROP COOPERVISION, INC. (US) 1985-04-02 US claimed
US-20250044289-A1 MOLECULARLY IMPRINTED POLYMER COATINGS AND SENSORS FOR BIODETECTION ORCA HOLDINGS LLC (US) 2025-02-06 US disclosed
EP-4409273-A1 MOLECULARLY IMPRINTED POLYMER COATINGS AND SENSORS FOR BIODETECTION Orca Holdings, LLC (US) 2024-08-07 EP disclosed
US-20240181430-A1 POROUS SORPTIVE SOLID PHASE MICROEXTRACTION DEVICES AND PREPARATION THEREOF MEMORIAL UNIVERSITY OF NEWFOUNDLAND (CA) 2024-06-06 US disclosed
EP-4294559-A1 POROUS SORPTIVE SOLID PHASE MICROEXTRACTION DEVICES AND PREPARATION THEREOF Memorial University of Newfoundland (CA) 2023-12-27 EP disclosed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO disclosed
EP-0106351-A2 Photopolymerizable photosensitive composition MITSUBISHI KASEI CORPORATION (JP) 1984-04-25 EP disclosed
US-4436887-A CONTACT LENSES, OXYGEN PERMEABILITY BAUSCH & LOMB INCORPORATED (US) 1984-03-13 US disclosed
US-4421841-A UNSATURATED POLYESTERS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-12-20 US disclosed
EP-0079721-A2 N-vinyl lactam-based biomedical devices and process for preparation thereof BAUSCH & LOMB INCORPORATED (US) 1983-05-25 EP disclosed
EP-0071236-A1 Photosensitive lithographic plate MITSUBISHI KASEI CORPORATION (JP) 1983-02-09 EP disclosed