Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476343 | 1.00 | PDE10A (0.44) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3476339 | 1.00 | PDE10A (0.44) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17610078 | 0.86 | GRIN2D (0.47) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22795923 | 0.80 | PDE10A (0.43) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22796105 | 0.80 | GRIN2D (0.43) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16174456 | 0.78 | ACACB (0.41) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16174457 | 0.78 | ACACB (0.41) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22660735 | 0.77 | GRIN2B (0.43) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22796039 | 0.76 | GRIN2D (0.45) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22796041 | 0.76 | GRIN2D (0.45) | PDE10AGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429998-B1 | 5-MEMBERED HETEROCYCLIC COMPOUND CYCLOPENTA[C]PYRROLYLALKYLCARBAMATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2013-11-27 | — | — | EP | disclosed |
| WO-2010130943-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND CYCLOPENTA[C]PYRROLYLALKYLCARBAMATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-11-18 | — | — | WO | disclosed |