Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477156 | 1.00 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL847916 | 0.93 | KDR (0.82) | KDRPDGFRB | |
| SCHEMBL836777 | 0.93 | KDR (0.82) | KDRPDGFRB | |
| SCHEMBL848442 | 0.93 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL836145 | 0.93 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL848359 | 0.93 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL833243 | 0.93 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL15810249 | 0.90 | KDR (0.66) | KDRPDGFRB | |
| SCHEMBL834833 | 0.90 | KDR (0.68) | KDRPDGFRB | |
| SCHEMBL834758 | 0.90 | KDR (0.70) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010078393-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| EP-2099757-A2 | SULFOXIMINES AS KINASE INHIBITORS | Allergan, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008061236-A2 | SULFOXIMINES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2008-05-22 | — | — | WO | disclosed |