⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310637 | 0.81 | — | — | |
| SCHEMBL11392187 | 0.69 | — | — | |
| SCHEMBL11738873 | 0.69 | MAPT (0.36) | — | |
| SCHEMBL4619040 | 0.67 | — | — | |
| SCHEMBL2301758 | 0.67 | — | — | |
| SCHEMBL7325221 | 0.66 | — | — | |
| SCHEMBL900229 | 0.65 | MAPT (0.33) | — | |
| Hydrochloric Acid SCHEMBL5239738 | 0.64 | MAPT (0.32) | — | |
| SCHEMBL8694798 | 0.61 | — | — | |
| SCHEMBL2904794 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105721-B1 | 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-INDAZOLES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-11 | — | — | EP | claimed |
| JP-62012761-A | — | — | None | — | — | JP | disclosed |
| CN-116947820-A | PRMT5-MTA inhibitors | 苏州浦合医药科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20100204278-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2010-08-12 | — | — | US | disclosed |
| EP-2099450-A2 | NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008051403-A2 | NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-0235567-B1 | Indazole compounds, their production, use and intermediates | SUMITOMO CHEMICAL CO (JP) | 1994-01-12 | — | — | EP | disclosed |
| EP-0275131-B1 | HERBICIDAL OXOINDANES AND TETRAHYDRONAPHTHALENES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-09-23 | — | — | EP | disclosed |
| US-4933480-A | 2-fluoro-4-halo-5-marcapto-phenyl-hydrazines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4831149-A | HERBICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0275131-A1 | Herbicidal oxoindanes and tetrahydronaphthalenes | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-07-20 | — | — | EP | disclosed |
| US-4752325-A | NEED CONTROL IN PADDY FIELD OF RICE PLANT | SUMITOMO CHEMICAL CO., LTD. (JP) | 1988-06-21 | — | — | US | disclosed |
| EP-0271170-A2 | Herbicidal substituted benzofurans and benzopyrans | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-15 | — | — | EP | disclosed |
| EP-0235567-A2 | Indazole compounds, their production, use and intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-09 | — | — | EP | disclosed |
| JP-S6212761-A | TETRAHYDROINDAZOLE DERIVATIVE, PRODUCTION THEREOF AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1987-01-21 | — | — | JP | disclosed |
| EP-0152890-A1 | 2-Substituted phenyl-3-chlorotetrahydro-2H-indazoles and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-28 | — | — | EP | disclosed |
| US-4169952-A | CONTROLLING PH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4139710-A | Preparation of hexahydroindazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4139710-A | Preparation of hexahydroindazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4139710-A | Preparation of hexahydroindazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-13 | — | — | US | disclosed |