SCHEMBL3477908

SCHEMBL3477908

COC(=O)[C@@H](O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H](C=O)OC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10511428 1.00 TDP1 (0.33) TDP1TSHRALDH1A1
SCHEMBL10510379 1.00 TDP1 (0.33) TDP1TSHRALDH1A1
SCHEMBL10510127 1.00 TDP1 (0.33) TDP1TSHRALDH1A1
SCHEMBL10511703 1.00 TDP1 (0.33) TDP1TSHRALDH1A1
SCHEMBL755228 0.83 TSHR (0.42) TDP1TSHRALDH1A1
SCHEMBL3431727 0.83 TDP1 (0.33) TDP1TSHRALDH1A1
SCHEMBL5674520 0.82 TSHR (0.32) TDP1TSHR
SCHEMBL10511725 0.81 TSHR (0.31) TDP1TSHR
SCHEMBL10508861 0.81 TSHR (0.31) TDP1TSHR
SCHEMBL10741886 0.81 TSHR (0.31) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553653-B Panaxadiol glycoside derivative and preparation method and application thereof 苏州济尔生物医药有限公司 2024-04-09 CN disclosed
WO-2021149587-A1 METHOD FOR PRODUCING GLUCURONIC ACID 池田食研株式会社 2021-07-29 WO disclosed
US-20100035857-A1 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS MERCK SHARP & DOHME CORP. 2010-02-11 US disclosed
EP-2124549-A1 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS Merck & Co., Inc. (US) 2009-12-02 EP disclosed
WO-2008085300-A1 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS MERCK & CO., INC. (US) 2008-07-17 WO disclosed
EP-1368363-A2 SYNTHESIS OF CHLOROPHENOL RED GLUCORONIC ACID Beckman Coulter, Inc. (US) 2003-12-10 EP disclosed
EP-0864582-B1 Hypolipidemic 1,4-benzothiazepine-1,-dioxides AVENTIS PHARMA GMBH (DE) 2003-06-04 EP disclosed
US-6534637-B2 Generation of phenolsulphonphthalein glucuronic acid for use as tool in cancer diagnosis BECKMAN COULTER, INC. 2003-03-18 US disclosed
WO-2002064605-A2 SYNTHESIS OF CHLOROPHENOL RED GLUCORONIC ACID BECKMAN COULTER, INC. (US) 2002-08-22 WO disclosed
US-20020115128-A1 Synthesis of chlorophenol red glucuronic acid BECKMAN COULTER, INC. 2002-08-22 US disclosed
EP-0597915-B1 A PROCESS FOR MAKING MORPHINE-6-GLUCURONIDE OR SUBSTITUTED MORPHINE-6-GLUCURONIDE SALFORD ULTRAFINE CHEM & RES (GB) 1998-11-11 EP disclosed
EP-0864582-A2 Hypolipidemic 1,4-benzothiazepine-1,-dioxides HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-16 EP disclosed
US-5629339-A CHRONIC VENOUS INSUFFICIENCY ADIR ET COMPAGNIE (FR) 1997-05-13 US disclosed
US-5621087-A ANALGESICS SALFORD ULTRAFINE CHEMICALS AND RESEARCH LIMITED (GB) 1997-04-15 US disclosed
EP-0597915-A1 A PROCESS FOR MAKING MORPHINE-6-GLUCURONIDE OR SUBSTITUTED MORPHINE-6-GLUCURONIDE SALFORD ULTRAFINE CHEMICALS AND RESEARCH LIMITED (GB) 1994-05-25 EP disclosed
US-5218097-A PROCESS FOR THE PREPARATION OF PROTECTED MONO-SUGAR AND OLIGO-SUGAR HALIDES CIBA-GEIGY CORPORATION (US) 1993-06-08 US disclosed
WO-1993003051-A1 A PROCESS FOR MAKING MORPHINE-6-GLUCURONIDE OR SUBSTITUTED MORPHINE-6-GLUCURONIDE SALFORD ULTRAFINE CHEMICALS AND RESEARCH LIMITED (GB) 1993-02-18 WO disclosed
EP-0373118-A2 Process for the preparation of glycosyl halides of protected mono- and oligo-saccharides CIBA-GEIGY AG (CH) 1990-06-13 EP disclosed
EP-0173462-B1 ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF SUNTORY LIMITED (JP) 1989-10-25 EP disclosed
EP-0173462-A2 Ellipticine derivative and production process thereof SUNTORY LIMITED (JP) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115128-A1 Synthesis of chlorophenol red glucuronic acid GUSB, UGT1A6, UGT1A7 TDP1 3341/4885TSHR 407/4885ALDH1A1 268/4885
US-20100035857-A1 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS NPC1L1, HMGCR, PCSK9 TDP1 3893/4885TSHR 4729/4885ALDH1A1 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.