Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107285 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL3477492 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL28092117 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL3477532 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL3628815 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL876115 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL28092116 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL7739780 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL236896 | 1.00 | TSHR (0.67) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL3478058 | 0.98 | TSHR (0.63) | TSHRNAAARAD52NPSR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396355-B1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN INC (US) | 2018-05-23 | — | — | EP | disclosed |
| US-8680172-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130245756-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | LILLY MING INTERNATIONAL, INC. | 2013-09-19 | — | — | US | disclosed |
| US-8430928-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120245684-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2012-09-27 | — | — | US | disclosed |
| US-8222360-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20100211170-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010093823-A2 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | WO | disclosed |