SCHEMBL3478136

SCHEMBL3478136

C=C(CC)C(=O)OCCCCCCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.69
NAAA Q02083 1/20 0.59
EPHX1 P07099 1/20 0.50
RAD52 P43351 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HCAR2 Q8TDS4 1/20 0.46
ALDH1A1 P00352 2/20 0.44
FAAH O00519 1/20 0.44
LMNA P02545 1/20 0.44
ACHE P22303 6/20 0.44
DGKA P23743 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375249 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL26413 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL3476008 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL11803516 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL374874 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL375676 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL3503795 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL3503962 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL3627611 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL27466436 1.00 TSHR (0.69) TSHRNAAAEPHX1RAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396355-B1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN INC (US) 2018-05-23 EP disclosed
US-8680172-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2014-03-25 US disclosed
US-20130245756-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS LILLY MING INTERNATIONAL, INC. 2013-09-19 US disclosed
US-8430928-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2013-04-30 US disclosed
US-20120245684-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2012-09-27 US disclosed
US-8222360-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2012-07-17 US disclosed
US-20100211170-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 US disclosed
WO-2010093823-A2 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 WO disclosed
CN-1168906-A Polyolefin resin composition and oriented film therefrom SUMITOMO CHEMICAL CO (JP) 1997-12-31 CN disclosed