SCHEMBL3478377

SCHEMBL3478377

O=CCC(CC=O)OP(=O)(O)O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.34
SMPD1 P17405 3/20 0.33
FDPS P14324 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4434843 0.78 MPI (0.38) MPISMPD1
SCHEMBL17923999 0.78 LPAR2 (0.36) SMPD1
SCHEMBL17964308 0.76 SMPD1 (0.34) SMPD1
SCHEMBL2725372 0.76 SMPD1 (0.35) MPISMPD1
SCHEMBL17964306 0.74 SMPD1 (0.36) SMPD1
SCHEMBL6045766 0.72 MPI (0.37) MPISMPD1
Glycerylphosphate SCHEMBL59773 0.70 SMPD1 (0.37) SMPD1FDPSBLMTDP1
SCHEMBL6429913 0.70 PTPN1 (0.38) MPI
SCHEMBL139867 0.70 PTPN1 (0.38) MPI
SCHEMBL7639200 0.70 PTPN1 (0.38) MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230078330-A1 HUMAN ANTI-DENGUE ANTIBODIES AND METHODS OF USE THEREFOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA PUBLIC CORPORATION 2023-03-16 US disclosed
WO-2021154530-A1 HUMAN ANTI-DENGUE ANTIBODIES AND METHODS OF USE THEREFOR VANDERBILT UNIVERSITY (US) 2021-08-05 WO disclosed
EP-3307069-B1 USE OF TELMISARTAN TO PREVENT AND TREAT GRAFT VERSUS HOST DISEASE AND OTHER ALLOIMMUNE AND AUTOIMMUNE DISEASES UNIV HACKENSACK MEDICAL CENTER (US) 2021-08-04 EP disclosed
EP-3307069-A1 USE OF TELMISARTAN TO PREVENT AND TREAT GRAFT VERSUS HOST DISEASE AND OTHER ALLOIMMUNE AND AUTOIMMUNE DISEASES Hackensack University Medical Center (US) 2018-04-18 EP disclosed
US-9937154-B2 Use of telmisartan to prevent and treat graft versus host disease and other alloimmune and autoimmune diseases Hackensak University Medical Center (US) 2018-04-10 US disclosed
WO-2016200694-A1 USE OF TELMISARTAN TO PREVENT AND TREAT GRAFT VERSUS HOST DISEASE AND OTHER ALLOIMMUNE AND AUTOIMMUNE DISEASES HACKENSACK UNIVERSITY MEDICAL CENTER (US) 2016-12-15 WO disclosed
US-20160361300-A1 USE OF TELMISARTAN TO PREVENT AND TREAT GRAFT VERSUS HOST DISEASE AND OTHER ALLOIMMUNE AND AUTOIMMUNE DISEASES HACKENSACK UNIVERSITY MEDICAL CENTER 2016-12-15 US disclosed
EP-1652928-B1 PLANT PRODUCING HYALURONIC ACID TOYO BOSEKI (JP) 2010-12-01 EP disclosed
US-7547819-B2 Plant producing hyaluronic acid TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-06-16 US disclosed
US-20060168690-A1 Plant producing hyaluronic acid RESEARCH CENTER OF TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-07-27 US disclosed
EP-1652928-A1 PLANT PRODUCING HYALURONIC ACID Toyo Boseki Kabushiki Kaisha (JP) 2006-05-03 EP disclosed
US-6699837-B2 HEPATOCYTE GROWTH FACTOR MANUFACTURED BY GENE RECOMBINATION; TREATMENT OF DEMENTIA, SENILE DEMENTIA OF ALZHEIMER TYPE, CEREBRAL STROKE, AND CEREBRAL INFARCTION NAKAMURA TOSHIKAZU (JP) 2004-03-02 US disclosed
EP-0722737-B1 Use of HGF for the preparation of a medicament against CNS disorders SUMITOMO PHARMA (JP) 2003-05-07 EP disclosed
US-20030060403-A1 THERAPEUTIC AGENT FOR DISORDER IN BRAIN AND NERVE NAKAMURA TOSHIKAZU (JP) 2003-03-27 US disclosed
US-20020049151-A1 Therapeutic approaches to diseases by suppression of the NURR subfamily of nuclear transcription factors BAYLOR COLLEGE OF MEDICINE 2002-04-25 US disclosed
US-6099857-A LIPID, VESICLE KIT; DRUG DELIVERY WASHINGTON UNIVERSITY (US) 2000-08-08 US disclosed
US-5766626-A VESICLE COMPOSITION FOR DELIVERING THERAPEUTIC AGENT TO TARGET BIOLOGICAL CELLS WASHINGTON UNIVERSITY (US) 1998-06-16 US disclosed
EP-0722737-A1 REMEDY FOR CRANIAL NERVE DISORDER SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1996-07-24 EP disclosed
WO-1995031183-A1 CELL MEMBRANE FUSION COMPOSITION AND METHOD WASHINGTON UNIVERSITY (US) 1995-11-23 WO disclosed