SCHEMBL3480295

SCHEMBL3480295

CCCCCN(CCCCC)C(C=Cc1ccccc1)CCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.38
HDAC3 O15379 2/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
BCHE P06276 3/20 0.36
ACHE P22303 2/20 0.36
KCNH2 Q12809 4/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 1/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2380256 0.78 EGFR (0.40) EGFRHDAC3HDAC4HDAC1HDAC7
SCHEMBL5981426 0.76 BCHE (0.39) EGFRHDAC3HDAC4HDAC1HDAC7
SCHEMBL10623750 0.75 MEN1 (0.40) EGFRMEN1KMT2ABCHEACHE
SCHEMBL10626695 0.75 MEN1 (0.40) EGFRMEN1KMT2ABCHEACHE
SCHEMBL10623959 0.75 MEN1 (0.40) EGFRMEN1KMT2ABCHEACHE
SCHEMBL10628611 0.75 MEN1 (0.40) EGFRMEN1KMT2ABCHEACHE
SCHEMBL2787289 0.74 HTR2A (0.42) EGFRHDAC3HDAC4HDAC1HDAC7
SCHEMBL489041 0.72 HDAC3 (0.41) EGFRHDAC3HDAC4HDAC1HDAC7
SCHEMBL27920575 0.72 HDAC3 (0.41) EGFRHDAC3HDAC4HDAC1HDAC7
SCHEMBL6859717 0.72 EGFR (0.42) EGFRHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2217674-B1 ELECTROACTIVE MATERIALS DU PONT (US) 2017-08-23 EP disclosed
US-9575423-B2 Electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-02-21 US disclosed
US-20150253682-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-09-10 US disclosed
CN-101331558-B Conjugated polymers, their preparation and use MERCK PATENT GMBH 2012-10-03 CN disclosed
CN-101331558-B Conjugated polymers, their preparation and use MERCK PATENT GMBH 2012-10-03 CN disclosed
US-7799875-B2 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2010-09-21 US disclosed
US-7799875-B2 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2010-09-21 US disclosed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 US disclosed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 US disclosed
CN-101331558-A Conjugated polymers, their preparation and use MERCK PATENT GMBH (DE) 2008-12-24 CN disclosed
CN-101331558-A Conjugated polymers, their preparation and use MERCK PATENT GMBH (DE) 2008-12-24 CN disclosed
EP-1961016-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE Merck Patent GmbH (DE) 2008-08-27 EP disclosed
WO-2007068325-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE MERCK PATENT GMBH (DE) 2007-06-21 WO disclosed