Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482632 | 0.92 | HCAR2 (0.39) | HCAR2TSHRATM | |
| SCHEMBL8733393 | 0.92 | HCAR2 (0.39) | HCAR2TSHRATM | |
| SCHEMBL9242825 | 0.85 | HCAR2 (0.52) | HCAR2TSHRKDM4EMAPTATM | |
| SCHEMBL8736762 | 0.85 | HCAR2 (0.52) | HCAR2TSHRKDM4EMAPTATM | |
| SCHEMBL9239924 | 0.85 | HCAR2 (0.48) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL9239913 | 0.85 | HCAR2 (0.48) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL9239888 | 0.84 | HCAR2 (0.50) | HCAR2ALDH1A1MAPTATM | |
| SCHEMBL9239895 | 0.84 | HCAR2 (0.50) | HCAR2ALDH1A1MAPTATM | |
| SCHEMBL10783950 | 0.83 | HCAR2 (0.46) | HCAR2ATM | |
| SCHEMBL7179299 | 0.83 | HCAR2 (0.46) | HCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-0722110-B1 | Water absorptive soft contact lens | MENICON CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| EP-0729041-B1 | Water-Absorptive soft contact lens | MENICON CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5741830-A | COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE | MENICON CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0729041-A2 | Water-Absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0722110-A2 | Water absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | HCAR2 2928/4885TSHR 4554/4885TP53 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.