Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740812 | 1.00 | HCAR2 (0.59) | HCAR2ACHEBACE1CHRM1AKR1A1 | |
| SCHEMBL9328098 | 1.00 | HCAR2 (0.59) | HCAR2ACHEBACE1CHRM1AKR1A1 | |
| SCHEMBL4583113 | 0.92 | HCAR2 (0.45) | HCAR2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9328093 | 0.92 | HCAR2 (0.45) | HCAR2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4583109 | 0.92 | HCAR2 (0.45) | HCAR2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3482317 | 0.89 | HCAR2 (0.55) | HCAR2ACHEBACE1ALDH1A1ATM | |
| SCHEMBL11407409 | 0.89 | HCAR2 (0.55) | HCAR2ACHEBACE1ALDH1A1ATM | |
| SCHEMBL20563886 | 0.89 | HCAR2 (0.46) | HCAR2ACHEBACE1CHRM1AKR1A1 | |
| SCHEMBL3482324 | 0.89 | HCAR2 (0.55) | HCAR2ACHEBACE1ALDH1A1ATM | |
| SCHEMBL7543926 | 0.86 | HCAR2 (0.55) | HCAR2CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109044985-A | Pharmaceutical preparation comprising one of corrosion skeleton or a variety of fumarates | 前进制药知识产权有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-102369001-A | Pharmaceutical formulation comprising one or more fumaric acid esters in an eroding matrix | FORWARD PHARMA AS | 2012-03-07 | — | — | CN | claimed |
| CN-102369000-A | Pharmaceutical compositions comprising one or more fumaric acid esters | FORWARD PHARMA AS | 2012-03-07 | — | — | CN | claimed |
| WO-2024225302-A1 | NOVEL FUMARIC ACID ESTER MONOMER, RESIN, AND FILM CONTAINING SAME | 東ソー株式会社 | 2024-10-31 | — | — | WO | disclosed |
| CN-118355062-A | Gas barrier film and packaging material | DIC株式会社 | 2024-07-16 | — | — | CN | disclosed |
| EP-3603954-B1 | POLYMER SUBSTRATE WITH HARD COAT LAYER | TEIJIN LTD (JP) | 2024-03-20 | — | — | EP | disclosed |
| US-11866564-B2 | Polymer substrate with hard coat layer | TEIJIN LIMITED (JP) | 2024-01-09 | — | — | US | disclosed |
| EP-3575333-B1 | ACTIVE-ENERGY-RAY-CURABLE AQUEOUS RESIN COMPOSITION AND UNDERCOAT AGENT FOR INORGANIC-MATERIAL THIN FILM | DAINIPPON INK & CHEMICALS (JP) | 2023-09-06 | — | — | EP | disclosed |
| EP-3486262-B1 | ACTIVE-ENERGY-RAY-CURABLE RESIN COMPOSITION AND METAL-THIN-FILM UNDERCOAT AGENT | DAINIPPON INK & CHEMICALS (JP) | 2023-05-10 | — | — | EP | disclosed |
| US-11306172-B2 | Active-energy-ray-curable resin composition and metal-thin-film undercoat agent | DIC CORPORATION (JP) | 2022-04-19 | — | — | US | disclosed |
| EP-3354455-B1 | POLYMER SUBSTRATE WITH HARDCOAT LAYER, AND MANUFACTURING METHOD FOR SAME | TEIJIN LTD (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20150284556-A1 | PHOTOPOLYMERIZABLE MOLDING RESIN COMPOSITION AND MOLDED MULTILAYER ARTICLE | DIC CORPORATION (JP) | 2015-10-08 | — | — | US | disclosed |
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| CN-102369001-A | Pharmaceutical formulation comprising one or more fumaric acid esters in an eroding matrix | FORWARD PHARMA AS | 2012-03-07 | — | — | CN | disclosed |
| CN-102369000-A | Pharmaceutical compositions comprising one or more fumaric acid esters | FORWARD PHARMA AS | 2012-03-07 | — | — | CN | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| US-20040096757-A1 | Photosensitive resin compositon, photosesitive resist for color filter, and process for producing color filter | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | HCAR2 2928/4885ACHE 3372/4885BACE1 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.