SCHEMBL3484857

SCHEMBL3484857

C=COC(=O)CC(C=C)CC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4280331 0.82 SLC22A6 (0.43) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL28806446 0.79 HDAC3 (0.40) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL31087096 0.76 FOLH1 (0.42) TSHRSLC22A6TDP1
SCHEMBL19506901 0.73
SCHEMBL7942709 0.72 SLC6A2 (0.30) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL7707787 0.72 SLC6A2 (0.41) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL6154882 0.72 SLC22A6 (0.38) SLC22A6
SCHEMBL29951485 0.72
SCHEMBL28518615 0.72
SCHEMBL29955089 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144122-A2 Powder conveyance device, image forming apparatus & process cartridge Ricoh Company, Limited (JP) 2010-01-13 EP disclosed