⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612930 | 0.78 | — | — | |
| SCHEMBL10361231 | 0.76 | — | — | |
| SCHEMBL4556938 | 0.74 | — | — | |
| SCHEMBL4159612 | 0.73 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL9171267 | 0.73 | — | — | |
| SCHEMBL17105684 | 0.72 | — | — | |
| SCHEMBL4436729 | 0.72 | — | — | |
| SCHEMBL8295314 | 0.72 | — | — | |
| SCHEMBL15856133 | 0.71 | TSHR (0.67) | — | |
| SCHEMBL20604083 | 0.71 | KMT2A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182990-A1 | DETECTION OF INFECTIOUS AGENT BASED ON RECOMBINASE POLYMERASE AMPLIFICATION COMBINED WITH A MAGNETIC FIELD-ENHANCED AGGLUTINATION | FRANCAIS DU SANG ETS (FR) | 2024-06-06 | — | — | US | disclosed |
| EP-4305198-A1 | DETECTION OF INFECTIOUS AGENT BASED ON RECOMBINASE POLYMERASE AMPLIFICATION COMBINED WITH A MAGNETIC FIELD-ENHANCED AGGLUTINATION | Etablissement Français du Sang (FR) | 2024-01-17 | — | — | EP | disclosed |
| US-11078229-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-08-03 | — | — | US | disclosed |
| US-20180265538-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2018-09-20 | — | — | US | disclosed |
| US-9896473-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | ETABLISSEMENT FRANCAIS DU SANG (FR) | 2018-02-20 | — | — | US | disclosed |
| CN-106588684-A | Synthesis method of N- allyl propargyl amides | 河南农业大学 | 2017-04-26 | — | — | CN | disclosed |
| EP-2834253-B1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-03-29 | — | — | EP | disclosed |
| US-20150158964-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2015-06-11 | — | — | US | disclosed |
| EP-2834253-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | Centre National de la Recherche Scientifique (CNRS) (FR) | 2015-02-11 | — | — | EP | disclosed |
| WO-2014037308-A1 | PROCESS FOR PREPARING N-H OR N-ALKYL 2-PROPYNAMIDE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-13 | — | — | WO | disclosed |
| EP-2189482-A1 | BLOCK POLYMER AND DEVICE | Canon Kabushiki Kaisha (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20090159856-A1 | BLOCK POLYMER AND DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-1084130-B1 | SUBSTITUTED FIVE MEMBERED HETEROCYCLIC COMPOUNDS, FUNGICIDAL COMPOSITIONS CONTAINING THEM AND METHODS OF MANUFACTURE THEREOF | MONSANTO TECHNOLOGY LLC (US) | 2002-09-04 | — | — | EP | disclosed |
| US-6291513-B1 | PYRROLINES, DIHYDROTHIOPHENES AND DIHYDROFURANS 3-SUBSTITUTED WITH CARBOXY, AMIDE OR THIO-DERIVATIVES | MONSANTO COMPANY | 2001-09-18 | — | — | US | disclosed |
| EP-1084130-A1 | SUBSTITUTED FIVE MEMBERED HETEROCYCLIC COMPOUNDS, FUNGICIDAL COMPOSITIONS CONTAINING THEM AND METHODS OF MANUFACTURE THEREOF | MONSANTO COMPANY (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6140511-A | DEHYDRATING 4-HYDROXY-4,5-DIMETHYL-2-TRIMETHYLSILANYL-DIHYDROTHIOPHENE-3-C ARBOXYLIC ACID ALLYLAMIDE | MONSANTO COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| WO-1999062915-A1 | SUBSTITUTED FIVE-MEMBERED HETEROCYCLIC COMPOUNDS, FUNGICIDAL COMPOSITIONS CONTAINING THEM AND METHODS OF MAKING THEREOF | MONSANTO COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0519427-B1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| EP-0552418-A1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0519427-A2 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |