SCHEMBL3485635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2768013	0.82	KDR (0.59)	TLK2PDPK1RETCDK2KDR
	SCHEMBL1538367	0.82	KDR (0.59)	TLK2PDPK1RETCDK2KDR
	SCHEMBL6389451	0.82	KDR (0.58)	PDPK1RETCDK2KDRCDK1
	SCHEMBL6389448	0.82	KDR (0.58)	PDPK1RETCDK2KDRCDK1
	SCHEMBL6390272	0.82	RET (0.62)	PDPK1RETKDRFGFR1FLT3
	SCHEMBL6390271	0.82	RET (0.62)	PDPK1RETKDRFGFR1FLT3
	SCHEMBL6389287	0.82	LRRK2 (0.62)	RETRPS6KA3PDGFRBLRRK2SIRT1
	SCHEMBL6389284	0.82	LRRK2 (0.62)	RETRPS6KA3PDGFRBLRRK2SIRT1
	SCHEMBL6393587	0.81	TLK2 (0.65)	TLK2PDPK1KDRCDK1FGFR1
	SCHEMBL6393582	0.81	TLK2 (0.65)	TLK2PDPK1KDRCDK1FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.