Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68530 | 0.88 | TYR (0.55) | HMGCRCYP3A4TYRNFE2L2MAOB | |
| SCHEMBL68531 | 0.88 | TYR (0.55) | HMGCRCYP3A4TYRNFE2L2MAOB | |
| SCHEMBL14798025 | 0.85 | CYP3A4 (0.51) | HMGCRCYP3A4TYRNFE2L2SNCA | |
| SCHEMBL28763191 | 0.85 | HMGCR (0.55) | HMGCRCYP3A4TYRNFE2L2MAOB | |
| Cis-Asarone SCHEMBL29655982 | 0.83 | HMGCR (1.00) | HMGCRCYP3A4TYRNFE2L2SNCA | |
| Cis-Asarone SCHEMBL528747 | 0.83 | HMGCR (1.00) | HMGCRCYP3A4TYRNFE2L2SNCA | |
| Trans-Asarone SCHEMBL940800 | 0.83 | HMGCR (1.00) | HMGCRCYP3A4TYRNFE2L2SNCA | |
| Trans-Asarone SCHEMBL29433647 | 0.83 | HMGCR (1.00) | HMGCRCYP3A4TYRNFE2L2SNCA | |
| Trans-Asarone SCHEMBL528746 | 0.83 | HMGCR (1.00) | HMGCRCYP3A4TYRNFE2L2SNCA | |
| SCHEMBL22361000 | 0.82 | CYP3A4 (0.52) | HMGCRCYP3A4TYRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108753912-B | High-throughput screening method for trans-anethole oxygenase mutant, mutant strain and mutant | 江南大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-108795889-B | Trans-anethol oxygenase mutant and mutant strain | 江南大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-108753742-B | Trans-anethole oxygenase mutant and mutant strain thereof | 江南大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-108753743-B | Trans-anethole oxygenase mutants and mutants | 江南大学 | 2020-11-03 | — | — | CN | disclosed |
| US-9131648-B2 | Genes encoding chavicol/eugenol synthase from the creosote bush Larrea tridentata | WASHINGTON STATE UNIVERSITY (US) | 2015-09-15 | — | — | US | disclosed |
| US-20100031398-A1 | GENES ENCODING CHAVICOL/EUGENOL SYNTHASE FROM THE CREOSOTE BUSH LARREA TRIDENTATA | WASHINGTON STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
| EP-2046110-A2 | GENES ENCODING CHAVICOL/EUGENOL SYNTHASE FROM THE CREOSOTE BUSH LARREA TRIDENTATA | Washington State University (US) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008005631-A2 | GENES ENCODING CHAVICOL/EUGENOL SYNTHASE FROM THE CREOSOTE BUSH LARREA TRIDENTATA | WASHINGTON STATE UNIVERSITY (US) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100031398-A1 | GENES ENCODING CHAVICOL/EUGENOL SYNTHASE FROM THE CREOSOTE BUSH LARREA TRIDENTATA | CNOT1, CRAT, LRAT | HMGCR 78/4885CYP3A4 305/4885TYR 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.