Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 14/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486610 | 0.92 | CACNA1B (0.48) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3486010 | 0.91 | CACNA1B (0.46) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3485373 | 0.89 | CACNA1B (0.47) | UBE2MDCUN1D1CACNA1BNR1I2CYP3A4 | |
| SCHEMBL3485692 | 0.89 | CACNA1B (0.46) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3486052 | 0.89 | CACNA1B (0.49) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3485902 | 0.89 | CACNA1B (0.46) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3485529 | 0.89 | CACNA1B (0.55) | UBE2MDCUN1D1CACNA1BNR1I2CYP3A4 | |
| SCHEMBL3486080 | 0.88 | CACNA1B (0.46) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3486812 | 0.87 | CACNA1B (0.46) | UBE2MDCUN1D1USP2ALDH1A1CACNA1B | |
| SCHEMBL3485704 | 0.87 | CACNA1B (0.48) | UBE2MDCUN1D1CACNA1BNR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791264-B2 | Benzenesulfonamide compounds and their use as blockers of calcium channels | PURDUE PHARMA L.P. (US) | 2014-07-29 | — | — | US | claimed |
| US-20100022595-A1 | Benzenesulfonamide Compounds and Their Use as Blockers of Calcium Channels | PURDUE PHARMA L.P. (CT) | 2010-01-28 | — | — | US | claimed |
| WO-2007118853-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS BLOCKERS OF CALCIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2007-10-25 | — | — | WO | claimed |
| US-8791264-B2 | Benzenesulfonamide compounds and their use as blockers of calcium channels | PURDUE PHARMA L.P. (US) | 2014-07-29 | — | — | US | disclosed |
| US-20100022595-A1 | Benzenesulfonamide Compounds and Their Use as Blockers of Calcium Channels | PURDUE PHARMA L.P. (CT) | 2010-01-28 | — | — | US | disclosed |
| WO-2007118853-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS BLOCKERS OF CALCIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022595-A1 | Benzenesulfonamide Compounds and Their Use as Blockers of Calcium Channels | CACNA1A, CACNA1E, CACNA1B | UBE2M 4024/4885DCUN1D1 3781/4885USP2 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.