SCHEMBL3487517

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15202711	0.85	PDGFRB (0.75)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL7838947	0.83	FGFR1 (1.00)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL7838948	0.83	FGFR1 (1.00)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL2196602	0.83	KDR (1.00)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL14519097	0.83	KDR (1.00)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL2196609	0.83	KDR (1.00)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL14519102	0.83	PDGFRB (0.75)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL14519101	0.83	PDGFRB (0.75)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL12335930	0.82	KDR (0.71)	KDRPDGFRBFGFR1SRCRET
	SCHEMBL1062998	0.82	KDR (1.00)	KDRPDGFRBFGFR1SRCRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.