⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500602 | 0.79 | — | — | |
| SCHEMBL2890343 | 0.72 | — | — | |
| SCHEMBL104270 | 0.72 | — | — | |
| SCHEMBL8749319 | 0.69 | — | — | |
| Bromide SCHEMBL7262629 | 0.69 | — | — | |
| SCHEMBL10799218 | 0.69 | — | — | |
| SCHEMBL234746 | 0.59 | — | — | |
| SCHEMBL9224764 | 0.57 | — | — | |
| SCHEMBL20576667 | 0.57 | — | — | |
| SCHEMBL3852652 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |
| US-7696166-B2 | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20080249002-A1 | CYCLOSPORIN ALKYNE ANALOGUES AND THEIR PHARMACEUTICAL USES | AMR TECHNOLOGY, INC. (US) | 2008-10-09 | — | — | US | disclosed |
| US-7378391-B2 | Cyclosporin alkyne analogues and their pharmaceutical uses | AMR TECHNOLOGY, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| US-20070232531-A1 | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders | AMR TECHNOLOGY, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| US-20060069016-A1 | Cyclosporin alkyne analogues and their pharmaceutical uses | AMR TECHNOLOGY, INC. (US) | 2006-03-30 | — | — | US | disclosed |