Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | GLUL | P15104 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142715 | 1.00 | HIF1A (0.63) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL7137204 | 1.00 | HIF1A (0.63) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL141852 | 1.00 | HIF1A (0.63) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL2087489 | 1.00 | HIF1A (0.63) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL5084683 | 0.99 | HIF1A (0.62) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL141360 | 0.98 | HIF1A (0.61) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL1535104 | 0.96 | HIF1A (0.63) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL29180381 | 0.96 | HIF1A (0.59) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL141828 | 0.94 | HIF1A (0.62) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL4450350 | 0.93 | HIF1A (0.61) | HIF1ASMN1; SMN2MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041772-B2 | FAT EMULSION CONTAINING A STEROID | GREEN CROSS CORPORATION (JP) | 1990-04-18 | — | — | EP | claimed |
| EP-0041772-B1 | FAT EMULSION CONTAINING A STEROID | GREEN CROSS CORPORATION (JP) | 1984-10-17 | — | — | EP | claimed |
| US-4340594-A | Fat emulsion containing steroid | THE GREEN CROSS CORPORATION (JP) | 1982-07-20 | — | — | US | claimed |
| EP-0041772-A2 | Fat emulsion containing a steroid | GREEN CROSS CORPORATION (JP) | 1981-12-16 | — | — | EP | claimed |
| US-20100080850-A1 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE | 2010-04-01 | — | — | US | disclosed |
| US-7592009-B2 | Polypeptide ligands for targeting cartilage and methods of use thereof | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2009-09-22 | — | — | US | disclosed |
| EP-2084275-A2 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008063291-A2 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2008-05-29 | — | — | WO | disclosed |
| US-20080118523-A1 | Chimeric polypeptide comprising tissue inhibitor of matrix metalloproteinases-3 (TIMP-3) for use in treatment and prevention of arthritic and degenerative joint disorders | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2008-05-22 | — | — | US | disclosed |
| EP-0331755-B2 | MEDICINE-CONTAINING FAT EMULSION OF THE TYPE PREPARED IMMEDIATELY BEFORE USE AND PROCESS FOR PREPARING MEDICINE-CONTAINING FAT EMULSION | TEIJIN LTD (JP) | 2003-02-05 | — | — | EP | disclosed |
| EP-0556394-B1 | LYOPHILIZED PREPARATION AND PRODUCTION THEREOF | NIPPON SHINYAKU CO LTD (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5651991-A | FATTY EMULSION OF NON-LIPOSOME PARTICLES CONTAINING DRUG IN CORE, AND HAVING LIPID SURFACE LAYER | NIPPON SHINYAKU CO. LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
| US-4448765-A | STABILIZED WITH A POLYMER | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-05-15 | — | — | US | disclosed |
| EP-0102265-A2 | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents | THE STOLLE RESEARCH AND DEVELOPMENT CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |
| EP-0007714-B1 | LIPOSOMES AND COMPOSITIONS CONTAINING THEM | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-09-14 | — | — | EP | disclosed |
| US-4347234-A | Medicinally useful, shaped mass of collagen resorbable in the body | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-08-31 | — | — | US | disclosed |
| US-4340594-A | Fat emulsion containing steroid | THE GREEN CROSS CORPORATION (JP) | 1982-07-20 | — | — | US | disclosed |
| EP-0041772-A2 | Fat emulsion containing a steroid | GREEN CROSS CORPORATION (JP) | 1981-12-16 | — | — | EP | disclosed |
| US-4291013-A | Medicinally useful, shaped mass of collagen resorbable in the body | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-22 | — | — | US | disclosed |
| EP-0007714-A1 | Liposomes and compositions containing them | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-02-06 | — | — | EP | disclosed |