Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489293 | 0.92 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL16415250 | 0.85 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL16415248 | 0.85 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL13473725 | 0.85 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL6886528 | 0.84 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL18867038 | 0.84 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL13473731 | 0.84 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL13500003 | 0.84 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL6886900 | 0.83 | ELANE (0.35) | — | |
| SCHEMBL18867206 | 0.83 | CYP3A4 (0.48) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293705-B2 | HCV protease inhibitors and uses thereof | AVILA THERAPEUTICS, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100041591-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041591-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | PEPD, CTRL, CTSC | CYP3A4 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.