Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493995 | 0.89 | GSK3B (0.52) | GSK3BNPC1RAB9AALDH1A1 | |
| SCHEMBL3490441 | 0.86 | GSK3B (0.67) | GSK3B | |
| SCHEMBL3491029 | 0.83 | GSK3B (0.60) | GSK3BNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL3492304 | 0.82 | GSK3B (0.59) | GSK3B | |
| SCHEMBL3493346 | 0.81 | GSK3B (0.58) | GSK3BNPC1RAB9AALDH1A1NOTUM | |
| SCHEMBL3490425 | 0.81 | GSK3B (0.55) | GSK3BNPC1RAB9A | |
| SCHEMBL3490840 | 0.81 | GSK3B (0.55) | GSK3BNOTUM | |
| SCHEMBL3490452 | 0.81 | GSK3B (0.53) | GSK3BRAB9ANOTUM | |
| SCHEMBL3491394 | 0.80 | GSK3B (0.56) | GSK3B | |
| SCHEMBL3492680 | 0.80 | GSK3B (0.58) | GSK3BNPC1RAB9AALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492378-B2 | GSK-3β inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20100069381-A1 | GSK-3BETAINHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069381-A1 | GSK-3BETAINHIBITOR | GSK3B, GSK3A, GSKIP | GSK3B 1/4885NPC1 1571/4885RAB9A 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.