SCHEMBL3494974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6367719	0.90	CACNA1H (0.39)	CACNA1HALDH1A1LMNAPOLBHPGD
	SCHEMBL3492777	0.87	PDE9A (0.54)	ALDH1A1POLBPDE9APDE1APDE1B
	SCHEMBL6367003	0.83	HCRTR1 (0.43)	CACNA1HALDH1A1LMNAPOLBHPGD
	SCHEMBL6371987	0.81	PDE9A (0.40)	ALDH1A1POLBHPGDPDE9APDE1A
	SCHEMBL6366070	0.81	PDE9A (0.44)	ALDH1A1L3MBTL1PDE9APDE1APDE1B
	SCHEMBL6368276	0.80	PIM1 (0.39)	ARIDO1LRRK2CLK2CLK3
	SCHEMBL6372381	0.80	NTRK1 (0.41)	IDO1LRRK2CLK2CLK3DYRK1A
	SCHEMBL3493363	0.79	PDE9A (0.55)	ALDH1A1POLBPDE9APDE1APDE1B
	SCHEMBL3493936	0.78	MEN1 (0.43)	ARIDO1LRRK2CLK2CLK3
	SCHEMBL6366628	0.76	PDE9A (0.53)	ARLMNAPDE9APDE1APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.