SCHEMBL349543

SCHEMBL349543

Cc1ccnc(-c2ccccn2)c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.56
NPC1 O15118 4/20 0.56
LMNA P02545 3/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CBFB Q13951 1/20 0.45
TP53 P04637 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 2/20 0.43
HTT P42858 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419032 1.00 KDM4E (0.56) KDM4ENPC1LMNACCR1CCR5
SCHEMBL29224593 0.98 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL28717929 0.98 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL27971454 0.98 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL29169401 0.98 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL8857926 0.98 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL14677966 0.98 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
Ethylene SCHEMBL28036074 0.96 KDM4E (0.53) KDM4ENPC1LMNACCR1CCR5
SCHEMBL4706782 0.93 KDM4E (0.50) KDM4ENPC1LMNACCR1CCR5
SCHEMBL29004412 0.84 KDM4E (0.43) KDM4ENPC1LMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119738466-A Reagent for analyzing dimethyl bipyridine molecular isomer, preparation method and analysis method thereof 宁波大学 2025-04-01 CN claimed
CN-116554009-B Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide 南京工业大学 2024-05-28 CN claimed
CN-117924180-A Indium-based hybrid metal halide crystal and preparation method and application thereof 中国科学院福建物质结构研究所 2024-04-26 CN claimed
CN-117659229-A Supported nickel catalyst and preparation method and application thereof 中国科学技术大学 2024-03-08 CN claimed
CN-117524751-A Preparation method of double-electric-layer supercapacitor 天津力神超电科技有限公司 2024-02-06 CN claimed
CN-116554009-A Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide 南京工业大学 2023-08-08 CN claimed
CN-116217395-A Preparation method of beta-carbonyl compound 黄淮学院 2023-06-06 CN claimed
CN-115959993-A Synthetic method of 2-aryl propionic acid compound 山东中医药大学 2023-04-14 CN claimed
CN-114149379-B Synthesis method for synthesizing multi-substituted oxazole product from simple aromatic carboxylic acid and cyano-substituted ester compound 温州大学 2023-03-10 CN claimed
CN-113336998-B Preparation method of benzocyclobutene side group cross-linked polyimide film with low dielectric and low heat conduction and micropores 中国科学院过程工程研究所 2022-10-21 CN claimed
EP-1747281-B1 ELECTROCHEMICAL ASSAY DEVICE AND RELATED METHODS AGAMATRIX INC (US) 2010-09-08 EP claimed
CN-100593419-C Methods and compositions for controlling ectoparasites HATCHTECH PTY LTD 2010-03-10 CN claimed
CN-100421799-C One-step production of 1,3-propanediol from ethylene oxide and syngas with a catalyst with a N-heterocyclic ligand SHELL INT RESEARCH (NL) 2008-10-01 CN claimed
CN-101132696-A Methods and compositions for controlling ectoparasites HATCHTECH PTY LTD (AU) 2008-02-27 CN claimed
CN-100355724-C Multidentate ligand, polynuclear metal complex, metal complex chain, metal complex aggregate structure, and method for producing same FUJITSU LTD (JP) 2007-12-19 CN claimed
WO-2007084380-A2 COMPOUNDS AND METHODS FOR NUCLEIC ACID MISMATCH DETECTION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-07-26 WO claimed
CN-1822854-A Methods and compositions for controlling ectoparasites HATCHTECH PTY LTD (AU) 2006-08-23 CN claimed
CN-1551801-A One-step production of 1,3-propanediol from ethylene oxide and syngas with a catalyst with a N-heterocyclic ligand ���ʿ����о����޹�˾ 2004-12-01 CN claimed
CN-1447717-A Polymerization Using In Situ Formed Late Transition Metal Catalyst Complexes EXXONMOBIL RES & ENG CO (US) 2003-10-08 CN claimed
CN-1036688-A PORPHYRIC INSECTICIDES UNIV ILLINOIS (US) 1989-11-01 CN claimed