⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741382 | 1.00 | — | — | |
| SCHEMBL17673060 | 0.92 | — | — | |
| SCHEMBL12425098 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL27263464 | 0.82 | — | — | |
| SCHEMBL8170965 | 0.79 | — | — | |
| SCHEMBL3647680 | 0.79 | — | — | |
| SCHEMBL12326042 | 0.77 | — | — | |
| SCHEMBL25007253 | 0.75 | — | — | |
| SCHEMBL15132378 | 0.75 | PIK3CD (0.32) | — | |
| SCHEMBL509596 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048393-A1 | Polar Modifier Systems for High Vinyl Block Copolymerization | DYNASOL ELASTÓMEROS, S.A. DE C.V. (MX) | 2020-02-13 | — | — | US | claimed |
| CN-108129657-A | A kind of synthetic method of biomass-based polyamide | 中国科学院大连化学物理研究所 | 2018-06-08 | — | — | CN | claimed |
| CN-112047953-B | Parthenolide-benzenesulfonyl furazan derivative and salt thereof, preparation method and application thereof | 天津尚德药缘科技股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-111825631-B | BE-43547 derivative and salt thereof, preparation method and application thereof in preparation of anticancer drugs | 新沂尚德药缘药业有限公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2023008470-A1 | FUSED-RING AMINE DERIVATIVE | 住友ファーマ株式会社 | 2023-02-02 | — | — | WO | disclosed |
| CN-112979474-B | Method for synthesizing 1, 6-hexanediamine by catalyzing 2, 5-dicyanofuran hydrogenation ring opening | 中国科学院大连化学物理研究所 | 2022-09-06 | — | — | CN | disclosed |
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |
| US-11384066-B1 | Heterocyclic compounds useful as aurora a selective inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-07-12 | — | — | US | disclosed |
| WO-2021238908-A1 | SALT AND CRYSTAL FORM OF HETEROARYL DERIVATIVE, AND PREPARATION METHOD THEREFOR | 上海翰森生物医药科技有限公司 | 2021-12-02 | — | — | WO | disclosed |
| CN-108473711-B | Use of Z-HFO-1, 1,1,4,4, 4-hexafluoro-2-butene in high temperature foaming applications | 科慕埃弗西有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113121573-A | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-112979474-A | Method for synthesizing 1, 6-hexanediamine by catalyzing 2, 5-dicyanofuran hydrogenation ring opening | 中国科学院大连化学物理研究所 | 2021-06-18 | — | — | CN | disclosed |
| CN-109776463-A | The preparation method of 2,5- furandicarboxylic acid dialkyl ester | 重庆化工职业学院 | 2019-05-21 | — | — | CN | disclosed |
| CN-108129657-A | A kind of synthetic method of biomass-based polyamide | 中国科学院大连化学物理研究所 | 2018-06-08 | — | — | CN | disclosed |
| US-20140303178-A1 | DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVES | MSD KK (JP) | 2014-10-09 | — | — | US | disclosed |
| US-8492378-B2 | GSK-3β inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| EP-2183239-B1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-22 | — | — | EP | disclosed |
| US-20100069381-A1 | GSK-3BETAINHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |