⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064874 | 0.97 | TSHR (1.00) | — | |
| SCHEMBL19193 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2107550 | 0.93 | — | — | |
| SCHEMBL4431010 | 0.93 | TSHR (0.93) | — | |
| SCHEMBL28881770 | 0.93 | — | — | |
| SCHEMBL1278490 | 0.93 | — | — | |
| Methyl Alcohol SCHEMBL584909 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL5086843 | 0.93 | — | — | |
| Water SCHEMBL1289230 | 0.93 | — | — | |
| SCHEMBL28736444 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400463-B | Preparation method of 2-n-propoxyacetyl chloride | 北京颖泰嘉和生物科技股份有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-109400463-B | Preparation method of 2-n-propoxyacetyl chloride | 北京颖泰嘉和生物科技股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| US-11149317-B2 | Methods for detecting epigenetic modifications | EXACT SCIENCES DEVELOPMENT COMPANY, LLC (US) | 2021-10-19 | — | — | US | disclosed |
| US-10808286-B2 | Methods for detecting epigenetic modifications | EXACT SCIENCES DEVELOPMENT COMPANY, LLC (US) | 2020-10-20 | — | — | US | disclosed |
| EP-3434791-B1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | EXACT SCIENCES DEV CO LLC (US) | 2020-05-27 | — | — | EP | disclosed |
| US-20190032149-A1 | METHODS FOR DETECTING EPIGENETIC MODIFICATIONS | JPMORGAN CHASE BANK, N.A. | 2019-01-31 | — | — | US | disclosed |
| EP-3434791-A1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | Exact Sciences Development Company, LLC (US) | 2019-01-30 | — | — | EP | disclosed |
| CN-108864076-A | glucosylceramide synthase inhibitors | 建新公司 | 2018-11-23 | — | — | CN | disclosed |
| US-20180327859-A1 | METHODS FOR DETECTING EPIGENETIC MODIFICATIONS | JPMORGAN CHASE BANK, N.A. | 2018-11-15 | — | — | US | disclosed |
| EP-2069527-B1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | EXACT SCIENCES DEV CO LLC (US) | 2018-06-06 | — | — | EP | disclosed |
| US-9982308-B2 | Methods for amplifying DNA from the promoter of the NDRG4 gene DNA obtained from a fecal sample | EXACT SCIENCES DEVELOPMENT COMPANY, LLC (US) | 2018-05-29 | — | — | US | disclosed |
| CN-104212795-B | Method for extracting total ribonucleic acid (RNA) of fish brain tissue | 北京市水产科学研究所 | 2017-04-26 | — | — | CN | disclosed |
| EP-2650377-B1 | Epigenetic change in selected genes and cancer | MDXHEALTH SA (BE) | 2016-12-21 | — | — | EP | disclosed |
| US-20150240318-A1 | Methods for Detecting Epigenetic Modifications | MDXHEALTH SA (BE) | 2015-08-27 | — | — | US | disclosed |
| US-8969046-B2 | Methods for detecting epigenetic modifications | MDXHEALTH SA (BE) | 2015-03-03 | — | — | US | disclosed |
| EP-2650377-A1 | Epigenetic change in selected genes and cancer | MDxHealth SA (BE) | 2013-10-16 | — | — | EP | disclosed |
| US-20100144836-A1 | Methods for Detecting Epigenetic Modifications | ONCOMETHYLOME SCIENCES SA (BE) | 2010-06-10 | — | — | US | disclosed |
| EP-2069527-A1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | Oncomethylome Sciences SA (BE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008084219-A1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | ONCOMETHYLOME SCIENCES SA (BE) | 2008-07-17 | — | — | WO | disclosed |