SCHEMBL3496986

SCHEMBL3496986

O=C=NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48
CPA1 P15085 5/20 0.46
CPA3 P15088 3/20 0.46
FOLH1 Q04609 1/20 0.46
CPB1 P15086 1/20 0.46
CPB2 Q96IY4 1/20 0.46
SRR Q9GZT4 2/20 0.44
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
SLC1A1 P43005 2/20 0.44
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MDM2 Q00987 1/20 0.43
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808578 1.00 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL4421756 1.00 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL27832950 0.98 CYP1A2 (0.50) CYP1A2ALPIPKMPTGS1XIAP
Water SCHEMBL27350729 0.98 CYP1A2 (0.50) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL27749682 0.89 ALPI (0.44) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL27556801 0.88 CYP1A2 (0.41) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL4727822 0.86 SLC7A5 (0.51) CYP1A2SLC7A5FOLH1
SCHEMBL12483915 0.86 SLC7A5 (0.51) CYP1A2SLC7A5FOLH1
SCHEMBL14338205 0.86 ALPI (0.46) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL30011914 0.86 EPHX1 (0.50) CYP1A2ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101010336-A Peptide antibiotics and process for preparing same BIOSOURCE PHARM INC (US) 2007-08-01 CN claimed
CN-1159758-A Peptides, methods for obtaining and derivatizing peptides and pharmaceutical compositions based on derivatised peptides V I DEIGIN (RU) 1997-09-17 CN claimed
US-20240116025-A1 HYBRID MATERIAL FOR CHROMATOGRAPHIC SEPARATIONS COMPRISING A SUPERFICIALLY POROUS CORE AND A SURROUNDING MATERIAL WATERS TECHNOLOGIES CORPORATION (US) 2024-04-11 US disclosed
CN-115109019-B Dehydrocostuslactone derivative, and preparation method and application thereof 上海医药工业研究院 2024-02-02 CN disclosed
CN-115232130-B APN and AKT double-target inhibitor and preparation method and application thereof 山东大学 2024-01-12 CN disclosed
US-20230294073-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2023-09-21 US disclosed
US-11642653-B2 Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material WATERS TECHNOLOGIES CORPORATION (US) 2023-05-09 US disclosed
EP-3539974-B1 METHOD FOR MODIFYING T CELL POPULATION UNIV OSAKA (JP) 2023-03-29 EP disclosed
CN-111936527-B Curable composition, liquid crystal sealant, liquid crystal panel, and method for producing liquid crystal panel 协立化学产业株式会社 2022-12-02 CN disclosed
CN-115232130-A APN and AKT double-target-point inhibitor and preparation method and application thereof 山东大学 2022-10-25 CN disclosed
CN-115109019-A Dehydrocostuslactone derivative, preparation method and application thereof 上海医药工业研究院 2022-09-27 CN disclosed
US-5428009-A Antibiotics, fungicides, and antiprotozoa agents MERCK & CO., INC. (US) 1995-06-27 US disclosed
US-5385884-A Water-soluble, injectible echinocandins; fungicides; antiprotozoa agents, yeasts MERCK & CO. INC. (US) 1995-01-31 US disclosed
CN-1027271-C Preparation method of n-statinib and n-cyclostatini polypeptide PFICER CO LTD (US) 1995-01-04 CN disclosed
US-5330973-A Fungicides, antiprotozoa agents MERCK & CO., INC. (US) 1994-07-19 US disclosed
EP-0448354-A2 Lipopeptide derivatives MERCK & CO. INC. (US) 1991-09-25 EP disclosed
EP-0448343-A2 Lipopeptide derivatives MERCK & CO. INC. (US) 1991-09-25 EP disclosed
CN-1049016-A New peptidase inhibitors MERRELL DOW PHARMA (US) 1991-02-06 CN disclosed
CN-87101499-A Preparation method of n-statinib and n-cyclostatini polypeptide 1988-05-11 CN disclosed
US-4618692-A ANTITUMOR AGENTS ASTA-WERKE AKTIENGESELLSCHAFT (DE) 1986-10-21 US disclosed