Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.96 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.96 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | PDXK | O00764 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridoxine SCHEMBL30877002 | 0.98 | HPGD (1.00) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL30267871 | 0.98 | HPGD (1.00) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL3506 | 0.98 | HPGD (1.00) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL2322958 | 0.98 | HPGD (1.00) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL8733421 | 0.96 | HPGD (0.96) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL4900587 | 0.96 | HPGD (0.96) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL42293 | 0.96 | KDM4E (0.96) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL5370659 | 0.96 | HPGD (0.96) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL5611277 | 0.96 | HPGD (0.96) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL7588196 | 0.96 | KDM4E (0.96) | HPGDKDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117064898-A | Application of pirenoxine sodium in preparing antitumor drug | 江西中医药大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-107920973-B | Surface modification composition | 株式会社LG生活健康 | 2021-05-07 | — | — | CN | disclosed |
| US-20100129913-A1 | POLIOMA VECTOR EXPRESSING LONG DOUBLE-STRANDED RNAS | VAN HOLST GERRIT JAN | 2010-05-27 | — | — | US | disclosed |
| EP-2035557-A2 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Phytovation B.V. (NL) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008000779-A2 | POLIOMA VECTOR EXPRESSING LONG DOUBLE-STRANDED RNAS | PHYTOVATION BV (NL) | 2008-01-03 | — | — | WO | disclosed |
| US-20050260166-A1 | Expressional enhancers from viruses | PHYTOVATION B.V. (NL) | 2005-11-24 | — | — | US | disclosed |
| CN-1659281-A | Antiviral therapy on the basis of RNA interference | VIRUVATION B V (NL) | 2005-08-24 | — | — | CN | disclosed |
| US-20050182010-A1 | Use of a nucleotide construct stably integrated in the genome of the target cells of the virus, which is able to produce a single transcript or multiple transcripts capable of forming a double-stranded RNA which inhibits replication of the virus | VIRUVATION B.V. (NL) | 2005-08-18 | — | — | US | disclosed |
| EP-1551981-A1 | EXPRESSIONAL ENHANCERS FROM VIRUSES | Phytovation B.V. (NL) | 2005-07-13 | — | — | EP | disclosed |
| EP-1495122-A1 | ANTIVIRAL THERAPY ON THE BASIS OF RNA INTERFERENCE | Viruvation B.V. (NL) | 2005-01-12 | — | — | EP | disclosed |
| WO-2004035796-A1 | EXPRESSIONAL ENHANCERS FROM VIRUSES | PHYTOVATION B.V. (NL) | 2004-04-29 | — | — | WO | disclosed |
| WO-2003087371-A1 | ANTIVIRAL THERAPY ON THE BASIS OF RNA INTERFERENCE | VIRUVATION B.V. (NL) | 2003-10-23 | — | — | WO | disclosed |