SCHEMBL3498646

SCHEMBL3498646

c1ccc2oc(-c3cc[nH]n3)nc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.54
ALDH1A1 P00352 10/20 0.54
RAB9A P51151 9/20 0.54
HPGD P15428 9/20 0.54
KDM4E B2RXH2 8/20 0.54
HSD17B10 Q99714 7/20 0.54
SMN1; SMN2 Q16637 7/20 0.54
TP53 P04637 6/20 0.54
MAPT P10636 5/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
PKM P14618 2/20 0.54
HCRTR1 O43613 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ATM Q13315 1/20 0.49
ALOX5 P09917 1/20 0.49
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531707 0.80 NPC1 (0.69) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL824375 0.80 NPC1 (0.69) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL970884 0.76 NPC1 (0.31) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL4806620 0.75 NPC1 (0.69) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL2485642 0.74 NPC1 (0.53) NPC1ALDH1A1RAB9AHPGDKDM4E
2-Phenylbenzo[D]Oxazole SCHEMBL31275269 0.73 NPC1 (0.70) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL171055 0.72 TOP2A (0.62) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL21674121 0.72 NPC1 (0.63) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL29504749 0.72 TOP2A (0.62) NPC1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL31170 0.72 NPC1 (0.81) NPC1ALDH1A1RAB9AHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1177845-C Method for producing 7-(phrazole-3-yl) benzoxazoles �����ɷ� 2004-12-01 CN claimed
CN-1418212-A Method for producing 7-(phrazole-3-yl) benzoxazoles BASF AG (DE) 2003-05-14 CN claimed
CN-1244865-A Substituted pyrazole-3-yl benzazoles BASF AK (DE) 2000-02-16 CN claimed
US-7737624-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-06-15 US disclosed
US-20090029092-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-01-29 US disclosed
US-20080233433-A1 electroluminescent device is provided and includes: a pair of electrodes; and at least one organic layer between the pair of electrodes, the at least one organic layer including a light-emitting layer. One of the at least one organic layers contains an iridium complex having a 5-membered heterocycle FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1652241-B8 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORP (JP) 2008-08-13 EP disclosed
EP-1652241-B1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORP (JP) 2008-06-18 EP disclosed
CN-100392509-C Process for producing microcapsule enclosing electrophoretic particle dispersion, microcapsule enclosing electrophoretic particle dispersion and reversible display medium containing the same TOYO INK MFG CO (JP) 2008-06-04 CN disclosed
CN-101146687-A Optical information recording medium FUJI PHOTO FILM CO LTD (JP) 2008-03-19 CN disclosed
EP-1862328-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2007-12-05 EP disclosed
US-7063901-B2 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. (JP) 2006-06-20 US disclosed
EP-1652241-A1 ORGANIC ELECTROLUMINESCENT DEVICE Fuji Photo Film Co., Ltd. (JP) 2006-05-03 EP disclosed
CN-1643445-A Process for producing microcapsule enclosing electrophoretic particle dispersion, microcapsule enclosing electrophoretic particle dispersion and reversible display medium containing the same TOYO INK MFG CO (JP) 2005-07-20 CN disclosed
CN-1606407-A Herbicidal mixture based on 7-pyrazolybenzoxazoles BASF AG (DE) 2005-04-13 CN disclosed
WO-2005013387-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJI PHOTO FILM CO., LTD. (JP) 2005-02-10 WO disclosed
CN-1177845-C Method for producing 7-(phrazole-3-yl) benzoxazoles �����ɷ� 2004-12-01 CN disclosed
US-20040065544-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2004-04-08 US disclosed
CN-1418212-A Method for producing 7-(phrazole-3-yl) benzoxazoles BASF AG (DE) 2003-05-14 CN disclosed
CN-1244865-A Substituted pyrazole-3-yl benzazoles BASF AK (DE) 2000-02-16 CN disclosed