SCHEMBL3499307

SCHEMBL3499307

C=CCCCCCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.65
MAOA P21397 1/20 0.60
MAOB P27338 1/20 0.60
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 1/20 0.53
CA12 O43570 6/20 0.52
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
CA9 Q16790 6/20 0.52
LMNA P02545 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
EPHX1 P07099 1/20 0.41
DRD2 P14416 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13012784 1.00 TDP1 (0.65) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL30304503 1.00 TDP1 (0.65) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL6454335 1.00 TDP1 (0.65) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL13817633 1.00 TDP1 (0.65) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL14756250 0.98 TDP1 (0.62) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL3637995 0.93 TDP1 (0.59) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL7827610 0.91 ABCC4 (0.56) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL24072259 0.86 TDP1 (0.49) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL360688 0.86 TDP1 (0.53) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL137629 0.86 TDP1 (0.85) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100297608-A1 Systems and Methods for CMOS-Compatible Silicon Nano-Wire Sensors with Biochemical and Cellular Interfaces YALE UNIVERSITY 2010-11-25 US claimed
EP-2097927-A1 SYSTEMS AND METHODS FOR CMOS-COMPATIBLE SILICON NANO-WIRE SENSORS WITH BIOCHEMICAL AND CELLULAR INTERFACES YALE UNIVERSITY (US) 2009-09-09 EP claimed
WO-2008153552-A9 SYSTEMS AND METHODS FOR CMOS-COMPATIBLE SILICON NANO-WIRE SENSORS WITH BIOCHEMICAL AND CELLULAR INTERFACES UNIV YALE (US) 2009-07-30 WO claimed
WO-2008153552-A1 SYSTEMS AND METHODS FOR CMOS-COMPATIBLE SILICON NANO-WIRE SENSORS WITH BIOCHEMICAL AND CELLULAR INTERFACES YALE UNIVERSITY (US) 2008-12-18 WO claimed
EP-4499641-A1 A3 ADENOSINE RECEPTOR POSITIVE ALLOSTERIC MODULATORS The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2025-02-05 EP disclosed
WO-2023192408-A1 A3 ADENOSINE RECEPTOR POSITIVE ALLOSTERIC MODULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-05 WO disclosed
US-10545142-B2 Calibration of nanostructure sensors YALE UNIVERSITY (US) 2020-01-28 US disclosed
US-9921216-B2 Nanoelectronic-enzyme linked immunosorbent assay system and method YALE UNIVERSITY (US) 2018-03-20 US disclosed
US-20170242000-A1 Calibration of Nanostructure Sensors YALE UNIVERSITY 2017-08-24 US disclosed
US-9599614-B2 Calibration of nanostructure sensors YALE UNIVERSITY (US) 2017-03-21 US disclosed
US-9316612-B2 Regenerative nanosensor devices YALE UNIVERSITY (US) 2016-04-19 US disclosed
US-20160054315-A1 NANOELECTRONIC-ENZYME LINKED IMMUNOSORBENT ASSAY SYSTEM AND METHOD YALE UNIVERSITY 2016-02-25 US disclosed
US-7829505-B2 Method for construction of oligonucleotide microarrays COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2010-11-09 US disclosed
US-20100184104-A1 NANOELECTRONIC-ENZYME LINKED IMMUNOSORBENT ASSAY SYSTEM AND METHOD YALE UNIVERSITY 2010-07-22 US disclosed
US-20100159572-A1 DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2010-06-24 US disclosed
CN-101592627-A The making integrated approach of multichannel high-sensitive biosensor SUZHOU INST NANO TECH & NANO B (CN) 2009-12-02 CN disclosed
EP-2097927-A1 SYSTEMS AND METHODS FOR CMOS-COMPATIBLE SILICON NANO-WIRE SENSORS WITH BIOCHEMICAL AND CELLULAR INTERFACES YALE UNIVERSITY (US) 2009-09-09 EP disclosed
WO-2008153552-A9 SYSTEMS AND METHODS FOR CMOS-COMPATIBLE SILICON NANO-WIRE SENSORS WITH BIOCHEMICAL AND CELLULAR INTERFACES UNIV YALE (US) 2009-07-30 WO disclosed
WO-2008153552-A1 SYSTEMS AND METHODS FOR CMOS-COMPATIBLE SILICON NANO-WIRE SENSORS WITH BIOCHEMICAL AND CELLULAR INTERFACES YALE UNIVERSITY (US) 2008-12-18 WO disclosed
US-20080146462-A1 Drilling fluid comprising an aqueous base fluid, a viscosifying biopolymer (cellulose/anionic/); a starch (potato or corn), and a chloride-free, amine-containing clay stabilizer(1,6-hexamine formate); effective to provide fluid with clay swelling of < 5% and shale disintegration of < 5%; oil/gas COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-06-19 US disclosed