Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL2566595 | 1.00 | TDP1 (0.45) | TDP1BACE1KDM4EALDH1A1ALOX5 | |
| Toluene SCHEMBL4286321 | 1.00 | TDP1 (0.45) | TDP1BACE1KDM4EALDH1A1ALOX5 | |
| Toluene SCHEMBL7558595 | 1.00 | TDP1 (0.45) | TDP1BACE1KDM4EALDH1A1ALOX5 | |
| Toluene SCHEMBL9422293 | 0.85 | BCHE (0.46) | CYP4F2CYP4A11ACHEIGF1RALOX15 | |
| Toluene SCHEMBL8122669 | 0.82 | TDP1 (0.48) | TDP1BACE1KDM4EALDH1A1ALOX5 | |
| Toluene SCHEMBL9561498 | 0.82 | TDP1 (0.48) | TDP1BACE1KDM4EALDH1A1ALOX5 | |
| Toluene SCHEMBL7791344 | 0.82 | TDP1 (0.48) | TDP1BACE1KDM4EALDH1A1ALOX5 | |
| Toluene SCHEMBL3692883 | 0.79 | TDP1 (0.65) | TDP1CYP4F2CYP4A11TSHRLMNA | |
| Toluene SCHEMBL1120065 | 0.79 | TDP1 (0.65) | TDP1CYP4F2CYP4A11TSHRLMNA | |
| Toluene SCHEMBL2589614 | 0.79 | TDP1 (0.65) | TDP1CYP4F2CYP4A11TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20100125059-A1 | 1-BIARYLAZETIDINONE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2010-05-20 | — | — | US | disclosed |
| EP-2133347-A1 | 1-BIARYLAZETIDINONE DERIVATIVES | Teijin Pharma Limited (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125059-A1 | 1-BIARYLAZETIDINONE DERIVATIVE | PCSK9, CYP46A1, HMGCR | TDP1 2062/4885BACE1 578/4885KDM4E 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.