SCHEMBL3503649

SCHEMBL3503649

Nc1nc2c(ncn2[C@H]2C[C@H](O)[C@@H](C(O)I)O2)c(=O)[nH]1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.56
STING1 Q86WV6 9/20 0.49
PDE3B Q13370 1/20 0.49
PDE3A Q14432 1/20 0.49
PNP P00491 1/20 0.48
P2RY2 P41231 1/20 0.47
P2RY4 P51582 1/20 0.47
P2RY6 Q15077 1/20 0.47
ADORA3 P0DMS8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30712246 0.94 POLB (0.58) POLBSTING1PDE3BPDE3APNP
SCHEMBL29546691 0.93 POLB (0.57) POLBSTING1PDE3BPDE3APNP
SCHEMBL3148826 0.91 POLB (0.55) POLBSTING1PDE3BPDE3APNP
SCHEMBL3501824 0.91 POLB (0.55) POLBSTING1PDE3BPDE3APNP
SCHEMBL28094790 0.88 POLB (0.59) POLBSTING1PDE3BPDE3APNP
SCHEMBL3779342 0.86 POLB (0.55) POLBSTING1PDE3BPDE3APNP
SCHEMBL10015775 0.84 POLB (0.59) POLBSTING1PDE3BPDE3APNP
SCHEMBL6914307 0.84 POLB (0.59) POLBSTING1PDE3BPDE3APNP
SCHEMBL13252942 0.84 POLB (0.59) POLBSTING1PDE3BPDE3APNP
SCHEMBL3692505 0.84 POLB (0.67) POLBSTING1PDE3BPDE3APNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109022351-B New application of recombinant human lysozyme 广州奇龙生物科技有限公司 2021-10-19 CN disclosed
US-9358234-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-06-07 US disclosed
US-20140037589-A1 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2014-02-06 US disclosed
US-8192732-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-06-05 US disclosed
US-20100183567-A1 Novel Mammalian Multipotent Stem Cells and Compositions, Methods of Preparation and Methods of Administration Thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2010-07-22 US disclosed
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US disclosed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US disclosed
EP-1471970-A4 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF UNIV ILLINOIS (US) 2006-08-02 EP disclosed
EP-1471970-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2004-11-03 EP disclosed
US-20030219898-A1 Novel mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-27 US disclosed
US-20030148513-A1 Novel mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2003-08-07 US disclosed
WO-2003060085-A2 MAMMALIAN NEURAL STEM CELLS, COMPOSITIONS AND USES THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed
WO-2003059276-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed