⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931 | 0.61 | — | — | |
| SCHEMBL2473025 | 0.58 | — | — | |
| SCHEMBL34874 | 0.55 | — | — | |
| Butadiene SCHEMBL28451 | 0.55 | — | — | |
| SCHEMBL11498161 | 0.55 | — | — | |
| Butadiene SCHEMBL43684 | 0.55 | — | — | |
| SCHEMBL17164676 | 0.55 | — | — | |
| Butadiene SCHEMBL2933701 | 0.55 | — | — | |
| SCHEMBL192 | 0.55 | — | — | |
| SCHEMBL3804487 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 868 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092831-A1 | Proteasome Inhibitors | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2024-03-21 | — | — | US | claimed |
| WO-2021072212-A1 | PROTEASOME INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-04-15 | — | — | WO | claimed |
| US-10624876-B2 | Derivatives of indole for the treatment of endometriosis | BIOKINESIS (FR) | 2020-04-21 | — | — | US | claimed |
| CN-110461858-A | Acyl nucleosides phosphonate ester, its prodrug and its purposes as drug | UNIV MONTPELLIER | 2019-11-15 | — | — | CN | claimed |
| EP-3116495-B1 | PIPERAZINE PHENOTHIAZINE DERIVATIVES FOR TREATING SPASTICITY | UNIV AIX MARSEILLE (FR) | 2019-11-06 | — | — | EP | claimed |
| US-20190275000-A1 | NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF ENDOMETRIOSIS | DIACCURATE (FR) | 2019-09-12 | — | — | US | claimed |
| EP-3529243-A1 | NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF ENDOMETRIOSIS | Biokinesis (FR) | 2019-08-28 | — | — | EP | claimed |
| US-20190169124-A1 | NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER, VIRAL INFECTIONS AND LUNG DISEASES | DIACCURATE (FR) | 2019-06-06 | — | — | US | claimed |
| EP-3191482-B1 | 1,2,3-THIADIAZOL-5YL-UREA DERIVATIVES, USE THEREOF FOR REGULATING PLANT SENESCENCE AND PREPARATIONS CONTAINING THESE DERIVATIVES | USTAV EXPERIMENTALNI BOTANIKY AV CR V V I (CZ) | 2019-03-27 | — | — | EP | claimed |
| US-10189782-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | BIOKINESIS (FR) | 2019-01-29 | — | — | US | claimed |
| CN-1085563-A | New peptide and preparation thereof and application | BASF AG (DE) | 1994-04-20 | — | — | CN | claimed |
| CN-1085223-A | The 17-beta substitution-4-azepine-5 α-androstane-3-one derivative | ERBA CARLO SPA (IT) | 1994-04-13 | — | — | CN | claimed |
| EP-0152910-B1 | PYRAZOLOPYRIDINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-07-12 | — | — | EP | claimed |
| CN-87103193-A | Steroid compounds containing a spiro ring in position 17, process and intermediates for their production, their use as medicaments and pharmaceutical compositions containing them | — | 1988-01-13 | — | — | CN | claimed |
| EP-0234178-A1 | New 8-substituted derivatives of an anhydrooctonic acid, methods for their preparation, pharmaceutical preparations containing these and intermediates | Astra Läkemedel Aktiebolag (SE) | 1987-09-02 | — | — | EP | claimed |
| WO-1987003878-A1 | NEW 8-SUBSTITUTED DERIVATIVES OF AN ANHYDROOCTONIC ACID, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE AND INTERMEDIATES | Astra Läkemedel Aktiebolag (SE) | 1987-07-02 | — | — | WO | claimed |
| US-4621089-A | Pyrazolopyridine derivatives and their use in treating inflammation and allergic conditions | BEECHAM GROUP P.L.C. (GB) | 1986-11-04 | — | — | US | claimed |
| EP-0195374-A2 | N-substituted 3,4-dihydropyrimidine derivatives, process for the production thereof and composition containing same for treating disorders of cardiovascular system | SUNTORY LIMITED (JP) | 1986-09-24 | — | — | EP | claimed |
| EP-0055602-A2 | Oxazolidinedione sulfide compounds | ELI LILLY AND COMPANY (US) | 1982-07-07 | — | — | EP | claimed |
| US-3976470-A | HERBICIDE | STAUFFER CHEMICAL COMPANY (US) | 1976-08-24 | — | — | US | claimed |