Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508636 | 1.00 | PPARG (0.50) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3506401 | 0.89 | PPARG (0.46) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3506407 | 0.89 | PPARG (0.46) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3511527 | 0.88 | PPARA (0.49) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3511529 | 0.88 | PPARA (0.49) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3507505 | 0.87 | PPARG (0.47) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3507500 | 0.87 | PPARG (0.47) | PPARGALOX5PSEN1PTGESTHRB | |
| SCHEMBL3510701 | 0.87 | S1PR5 (0.46) | PPARGALOX5PSEN1PTGESS1PR5 | |
| SCHEMBL3510699 | 0.87 | S1PR5 (0.46) | PPARGALOX5PSEN1PTGESS1PR5 | |
| SCHEMBL3510250 | 0.86 | PPARG (0.46) | PPARGALOX5PSEN1PTGESTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-1661879-A1 | DIPHENYL ETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | PPARG, PPARD, PPARA | PPARG 1/4885ALOX5 884/4885PSEN1 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.