Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509493 | 0.90 | PTPN1 (0.55) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8550939 | 0.89 | MAOB (0.61) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8546401 | 0.87 | PTPN1 (0.59) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL3507851 | 0.84 | PPARG (0.55) | PTPN1PPARGPPARAPPARD | |
| SCHEMBL8547195 | 0.84 | PTPN1 (0.56) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8547203 | 0.84 | PTPN1 (0.56) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8547205 | 0.84 | PTPN1 (0.56) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4674437 | 0.83 | PPARG (0.69) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8546484 | 0.83 | PTPN1 (0.57) | PTPN1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8546485 | 0.83 | PTPN1 (0.57) | PTPN1PPARGPPARACYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-1661879-A1 | DIPHENYL ETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | PPARG, PPARD, PPARA | PTPN1 1148/4885PPARG 1/4885PPARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.