Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31527632 | 0.83 | ATM (0.31) | DPP4 | |
| SCHEMBL26607531 | 0.83 | ATM (0.31) | DPP4 | |
| SCHEMBL27156471 | 0.83 | ATM (0.31) | DPP4 | |
| SCHEMBL4102771 | 0.83 | ATM (0.31) | DPP4 | |
| SCHEMBL1759463 | 0.83 | ATM (0.31) | DPP4 | |
| SCHEMBL30985474 | 0.83 | ATM (0.31) | DPP4 | |
| SCHEMBL3298331 | 0.75 | PIK3CA (0.33) | CFDDPP4 | |
| SCHEMBL3298328 | 0.75 | PIK3CA (0.33) | CFDDPP4 | |
| SCHEMBL15145225 | 0.75 | PIK3CA (0.33) | CFDDPP4 | |
| SCHEMBL26112319 | 0.75 | PIK3CA (0.33) | CFDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2505579-B1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2014-11-05 | — | — | EP | disclosed |
| EP-2792672-A2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | AstraZeneca AB (SE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2505578-B1 | Methods and Compounds for Producing Dipeptidyl Peptidase IV Inhibitors and Intermediates thereof | ASTRAZENECA AB (SE) | 2014-09-24 | — | — | EP | disclosed |
| EP-2517706-B1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2014-06-25 | — | — | EP | disclosed |
| EP-1581487-B1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | ASTRAZENECA AB (SE) | 2014-06-04 | — | — | EP | disclosed |
| US-20130012723-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2517706-A2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | Bristol-Myers Squibb Company (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-2505579-A2 | Methods and compounds for producing dipeptidyl peptidase iv inhibitors and intermediates thereof | Bristol-Myers Squibb Company (US) | 2012-10-03 | — | — | EP | disclosed |
| EP-2505578-A2 | Methods and Compounds for Producing Dipeptidyl Peptidase IV Inhibitors and Intermediates thereof | Bristol-Myers Squibb Company (US) | 2012-10-03 | — | — | EP | disclosed |
| US-8278462-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100274025-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
| US-7705033-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-20090018311-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | US | disclosed |
| US-7420079-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| EP-1581487-A4 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1658066-A2 | ADAMANTYLGLYCINE- BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FOR THE TREATMENT OF DIABETES | Bristol-Myers Squibb Company (US) | 2006-05-24 | — | — | EP | disclosed |
| EP-1581487-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | Bristol-Myers Squibb Company (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20050090539-A1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2005-04-28 | — | — | US | disclosed |
| WO-2005012249-A2 | ADAMANTYGLYCINE- BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FOR THE TREATMENT OF DIABETES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-10 | — | — | WO | disclosed |
| WO-2004052850-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274025-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | DPP4, DPP3, DPP8 | CFD 2963/4885DPP4 1/4885GABRR1 3875/4885 |
| US-20050090539-A1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | DPP4, DPP3, DPP8 | CFD 2963/4885DPP4 1/4885GABRR1 3875/4885 |
| US-20090018311-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | DPP4, DPP3, DPP8 | CFD 2963/4885DPP4 1/4885GABRR1 3875/4885 |
| US-20130012723-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | DPP4, DPP3, DPP8 | CFD 2963/4885DPP4 1/4885GABRR1 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.