Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL6894104 | 0.90 | TSHR (0.43) | TSHRCPT2CPT1AALDH1A1LMNA | |
| Glycinebetaine SCHEMBL28110612 | 0.88 | TSHR (0.42) | TSHRCPT2CPT1AALDH1A1LMNA | |
| Glycinebetaine SCHEMBL9116728 | 0.85 | TSHR (0.48) | TSHRCPT2CPT1AALDH1A1LMNA | |
| Betaine SCHEMBL31467313 | 0.84 | — | — | |
| Glycinebetaine SCHEMBL7739 | 0.84 | — | — | |
| Glycinebetaine SCHEMBL4900209 | 0.84 | — | — | |
| Glycinebetaine SCHEMBL2803780 | 0.84 | TSHR (0.53) | TSHRCPT2CPT1AALDH1A1LMNA | |
| Glycinebetaine SCHEMBL8678519 | 0.84 | TSHR (0.53) | TSHRCPT2CPT1AALDH1A1LMNA | |
| Glycinebetaine SCHEMBL2016478 | 0.82 | TSHR (0.46) | TSHRCPT2CPT1AALDH1A1LMNA | |
| Glycinebetaine SCHEMBL8408471 | 0.82 | TSHR (0.37) | TSHRCPT2CPT1AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251013-B1 | Inkjet recording sheet | FUJI PHOTO FILM CO LTD (JP) | 2006-04-12 | — | — | EP | claimed |
| US-6777039-B2 | APPLYING FIRST COATING (PH < OR = 5) OF POLYVINYL ALCOHOL, NONIONIC OR AMPHOTERIC SURFACTANT, HIGH BOILING SOLVENT, CATIONIC RESIN AND SILICA; APPLYING A SECOND COATING (PH > OR = 8.5) OF A CROSSLINKING AGENT BEFORE FULLY DRYING | FUJI PHOTO FILM CO., LTD. (JP) | 2004-08-17 | — | — | US | claimed |
| US-20030104175-A1 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. | 2003-06-05 | — | — | US | claimed |
| EP-1251013-A2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-23 | — | — | EP | claimed |
| US-7754297-B2 | Ink jet recording sheet | FUJIFILM CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-7399508-B2 | Recording medium | FUJIFILM CORPORATION (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20070237911-A1 | Coating liquid for ink receiving layer, production method thereof, ink jet recording medium and production method thereof | FUJIFILM CORPORATION (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1481812-B1 | Recording medium | FUJI PHOTO FILM CO LTD (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1422071-B1 | Ink jet recording sheet | FUJI PHOTO FILM CO LTD (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1251013-B1 | Inkjet recording sheet | FUJI PHOTO FILM CO LTD (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20050270357-A1 | Preparation method of inkjet recording paper | FUJI PHOTO FILM CO., LTD. | 2005-12-08 | — | — | US | disclosed |
| EP-1602501-A2 | Preparation method of inkjet recording paper | Fuji Photo Film Co., Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20040241347-A1 | Recording medium | FUJI PHOTO FILM CO., LTD. | 2004-12-02 | — | — | US | disclosed |
| EP-1481812-A2 | Recording medium | FUJI PHOTO FILM CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6777039-B2 | APPLYING FIRST COATING (PH < OR = 5) OF POLYVINYL ALCOHOL, NONIONIC OR AMPHOTERIC SURFACTANT, HIGH BOILING SOLVENT, CATIONIC RESIN AND SILICA; APPLYING A SECOND COATING (PH > OR = 8.5) OF A CROSSLINKING AGENT BEFORE FULLY DRYING | FUJI PHOTO FILM CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040101640-A1 | Ink jet recording sheet | FUJI PHOTO FILM CO., LTD. | 2004-05-27 | — | — | US | disclosed |
| EP-1422071-A1 | Ink jet recording sheet | Fuji Photo Film Co., Ltd. (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-20030104175-A1 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. | 2003-06-05 | — | — | US | disclosed |
| EP-1251013-A2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-20020045034-A1 | Ink-jet recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2002-04-18 | — | — | US | disclosed |