Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017617 | 0.84 | KDR (0.65) | KDRBRAF | |
| SCHEMBL14017830 | 0.81 | TRPV1 (0.52) | KDM4ERAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL14018401 | 0.80 | ABL1 (0.52) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL14017622 | 0.78 | CYP2C9 (0.52) | KDM4ERAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL14017623 | 0.77 | TRPV1 (0.47) | KDM4ERAB9ASMN1; SMN2NPC1THRB | |
| SCHEMBL4670192 | 0.76 | KDR (0.70) | RAB9ANPC1MAPTKDRHTT | |
| SCHEMBL3511551 | 0.73 | MAOB (0.38) | KDM4ESMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL14017653 | 0.73 | CYP2C9 (0.52) | TRPV1KDRBRAF | |
| SCHEMBL2324173 | 0.73 | MAPT (0.61) | KDM4ERAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL3378722 | 0.73 | TRPV1 (0.48) | KDM4ESMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137309-A1 | FUNGICIDES PHENYL-PYRIMIDNYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | claimed |
| EP-2155713-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | Bayer CropScience SA (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008138992-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-11-20 | — | — | WO | claimed |
| US-20100137309-A1 | FUNGICIDES PHENYL-PYRIMIDNYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-2155713-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | Bayer CropScience SA (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008138992-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137309-A1 | FUNGICIDES PHENYL-PYRIMIDNYL-AMINO DERIVATIVES | CYP1A1, CYP1A2, PAH | KDM4E 444/4885RAB9A 555/4885SMN1; SMN2 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.