Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515948 | 1.00 | HPGD (0.56) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL3516107 | 0.94 | HPGD (0.61) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL3516102 | 0.94 | HPGD (0.61) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL12880104 | 0.79 | HPGD (0.56) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL2625209 | 0.79 | HPGD (0.56) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL3389880 | 0.79 | HPGD (0.61) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL65930 | 0.78 | CYP1A2 (0.61) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL265577 | 0.78 | CYP1A2 (0.61) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL22066481 | 0.78 | HPGD (0.59) | HPGDCYP3A4TSHRMAPK1NPC1 | |
| SCHEMBL265135 | 0.78 | CYP1A2 (0.61) | HPGDCYP3A4TSHRMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |