Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245516 | 0.89 | ATM (0.74) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL7571698 | 0.89 | ATM (0.74) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL22067782 | 0.89 | ATM (0.74) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL15751610 | 0.89 | ATM (0.74) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL5654908 | 0.89 | ATM (0.74) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3518733 | 0.89 | ATM (0.74) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3513704 | 0.85 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3515210 | 0.85 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL7536955 | 0.85 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL10498427 | 0.85 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |