SCHEMBL3516653

SCHEMBL3516653

NC(=O)CC1=Cc2ccccc2NN=C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8329648 0.86 AKR1B1 (0.36) KDM4EALDH1A1
SCHEMBL8801323 0.85 NR4A2 (0.35)
SCHEMBL3501047 0.76 POLB (0.31)
SCHEMBL8686344 0.73 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL3519587 0.71 GAA (0.31) ALDH1A1
SCHEMBL10875377 0.71 CCNC (0.31)
SCHEMBL8801321 0.71 EPHX1 (0.36)
SCHEMBL3688542 0.70 TSHR (0.31)
SCHEMBL6743139 0.70 GAA (0.32) ALDH1A1
SCHEMBL6268407 0.70 F2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113648423-B Amphiphilic conjugate anti-tumor nano-drug, preparation method thereof, nano-assembly and application 南方医科大学 2022-11-22 CN disclosed
CN-113648423-A Amphiphilic conjugate anti-tumor nano-drug, preparation method thereof, nano-assembly and application 南方医科大学 2021-11-16 CN disclosed
WO-2010057028-A9 TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR LINK MEDICINE CORPORATION (US) 2010-09-02 WO disclosed
WO-2010057028-A2 TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR LINK MEDICINE CORPORATION (US) 2010-05-20 WO disclosed
EP-2155197-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES Link Medicine Corporation (US) 2010-02-24 EP disclosed
WO-2008112525-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES LINK MEDICINE CORPORATION (US) 2008-09-18 WO disclosed
WO-2005089515-A9 METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES BRIGHAM & WOMENS HOSPITAL (US) 2006-01-26 WO disclosed
WO-2005089515-A2 METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2005-09-29 WO disclosed