Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 6/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517021 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1TDP1UBE2NKDM4A | |
| SCHEMBL10973438 | 0.80 | KDM4A (0.36) | KDM4EALDH1A1UBE2NKDM4AKDM4C | |
| SCHEMBL10973452 | 0.80 | KDM4A (0.36) | KDM4EALDH1A1UBE2NKDM4AKDM4C | |
| SCHEMBL3516699 | 0.77 | FNTA (0.32) | — | |
| SCHEMBL3516588 | 0.77 | HDAC1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL3516594 | 0.77 | HDAC1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL3516694 | 0.77 | FNTA (0.32) | — | |
| SCHEMBL3516372 | 0.75 | CA1 (0.43) | KDM4AKDM4CPHF8KDM2A | |
| SCHEMBL3516367 | 0.75 | CA1 (0.43) | KDM4AKDM4CPHF8KDM2A | |
| SCHEMBL3518737 | 0.73 | FNTA (0.47) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |