Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.78 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731549 | 0.90 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1 | |
| SCHEMBL13732139 | 0.90 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1 | |
| SCHEMBL3518342 | 0.89 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1 | |
| SCHEMBL3520350 | 0.88 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3516204 | 0.86 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1 | |
| SCHEMBL3517989 | 0.86 | HSP90AA1 (0.83) | HSP90AA1HSP90AB1 | |
| SCHEMBL3518284 | 0.85 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL13050643 | 0.85 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3516184 | 0.83 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 | |
| SCHEMBL3519254 | 0.82 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219448-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | Myriad Pharmaceuticals, Inc. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065035-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | MYRIAD GENETICS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |